Combined liver-kidney transplantation with delayed kidney implantation: A case report

被引:1
作者
Bouari, Sarah [1 ]
Polak, Wojciech G. [1 ]
van de Wetering, Jacqueline [2 ]
Metselaar, Herold J. [3 ]
IJzermans, Jan N. M. [1 ]
Minnee, Robert C. [1 ,4 ]
机构
[1] Erasmus MC Univ, Dept Surg, Div HPB & Transplant Surg, Transplant Inst, Rotterdam, Netherlands
[2] Erasmus MC Univ, Dept Internal Med, Sect Nephrol & Transplantat, Transplant Inst, Rotterdam, Netherlands
[3] Erasmus MC Univ, Dept Gastroenterol & Hepatol, Transplant Inst, Rotterdam, Netherlands
[4] Dept Surg, Div HPB & Transplant Surg, Dr Molewaterpl 40, NL-3015 GD Rotterdam, Netherlands
关键词
Combined liver kidney transplantation; Delayed kidney implantation; Liver transplantation; Kidney transplantation; Case report;
D O I
10.1016/j.ijscr.2023.108276
中图分类号
R61 [外科手术学];
学科分类号
摘要
Introduction: In rare cases, patients require a combined liver-kidney transplant. However, the peri-and postoperative care of liver transplant recipients differs from kidney transplant recipients, which can lead to conflicts of interest. In the case of poor coagulation status and/or instable hemodynamics of the patient, liver transplantation, followed by delayed kidney transplantation can lead to better postoperative recovery. Presentation of case: In our case report, we present a 48-year old man with Alagille syndrome and IgA nephropathy with bilirubin-associated acute kidney injury, causing him to develop both end-stage liver and kidney disease. He underwent a combined liver-kidney transplant as the first patient in the Netherlands, in which the donor kidney was transplanted one day after the liver transplantation. One-year post-transplant patient is in good clinical condition, with normal liver function and an eGFR of 57 ml/min. Conclusion: Combined liver-kidney transplantation with delayed kidney implantation in a medical center with no previous experience with this technique is feasible and safe. This could be better for both the patient and the kidney graft.
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页数:3
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