Screening approaches to cardiac amyloidosis in different clinical settings: Current practice and future perspectives

被引：4

作者：

Caponetti, Angelo Giuseppe ^{[1
,2
]}

Accietto, Antonella ^{[1
,2
]}

Saturi, Giulia ^{[1
,2
]}

Ponziani, Alberto ^{[1
,2
]}

Sguazzotti, Maurizio ^{[1
,2
]}

Massa, Paolo ^{[1
,2
]}

Giovannetti, Alessandro ^{[1
,2
]}

Ditaranto, Raffaello ^{[1
,2
]}

Parisi, Vanda ^{[1
,2
]}

Leone, Ornella ^{[3
]}

Guaraldi, Pietro ^{[4
]}

Cortelli, Pietro ^{[4
,5
]}

Gagliardi, Christian ^{[1
,6
]}

Longhi, Simone ^{[1
,6
]}

Galie, Nazzareno ^{[1
,2
]}

Biagini, Elena ^{[1
,6
]}

机构：

[1] Univ Bologna, Cardiac Thorac & Vasc Dept, Cardiol Unit, IRCCS Azienda Osped, Bologna, Italy

[2] Univ Bologna, Dept Expt Diagnost & Specialty Med, Bologna, Italy

[3] Univ Bologna, Dept Pathol, Cardiovasc & Cardiac Transplant Pathol Unit, IRCCS Azienda Osped, Bologna, Italy

[4] IRCCS Ist Sci Neurol Bologna, Bologna, Italy

[5] Univ Bologna, Dept Biomed & NeuroMotor Sci DiBiNeM, Alma Mater Studiorum, Bologna, Italy

[6] European Reference Network Rare Low Prevalence &, Bologna, Italy

来源：

FRONTIERS IN CARDIOVASCULAR MEDICINE | 2023年 / 10卷

关键词：

cardiac amyloidosis; heart failure; ATTR; AL; screening; aortic stenosis; nuclear medicine; PRESERVED EJECTION FRACTION; HEART-FAILURE; TRANSTHYRETIN AMYLOIDOSIS; CONDUCTION SYSTEM; AORTIC-STENOSIS; LIGHT-CHAIN; DIAGNOSIS; ECHOCARDIOGRAPHY; ASSOCIATION; ARRHYTHMIAS;

D O I：

10.3389/fcvm.2023.1146725

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cardiac amyloidosis is a serious and progressive infiltrative disease caused by the deposition of amyloid fibrils in the heart. In the last years, a significant increase in the diagnosis rate has been observed owing to a greater awareness of its broad clinical presentation. Cardiac amyloidosis is frequently associated to specific clinical and instrumental features, so called "red flags", and it appears to occur more commonly in particular clinical settings such as multidistrict orthopedic conditions, aortic valve stenosis, heart failure with preserved or mildly reduced ejection fraction, arrhythmias, plasma cell disorders. Multimodality approach and new developed techniques such PET fluorine tracers or artificial intelligence may contribute to strike up extensive screening programs for an early recognition of the disease.

引用

页数：10

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