The Influence of Myopia on the Foveal Avascular Zone and Density of Blood Vessels of the Macula-An OCTA Study

被引:10
作者
Zivkovic, Maja L. J. [1 ,2 ]
Lazic, Lazar [2 ]
Zlatanovic, Marko [1 ,2 ]
Zlatanovic, Nevena [3 ]
Brzakovic, Mladen [4 ]
Jovanovic, Mihailo [5 ]
Barisic, Sava [6 ]
Darabus, Diana-Maria [7 ]
机构
[1] Clin Ctr Nis, Ophthalmol Clin, Bulevar Dr Zorana Dindica 48, Nish 18000, Serbia
[2] Univ Nis, Fac Med, Dept Ophthalmol, Bulevar Dr Zorana Dindica 81, Nish 18000, Serbia
[3] Community Hlth Ctr Nis Nis, Vojvode Tankosica 15, Nish 18000, Serbia
[4] Special Hosp Ophthalmol Clin Maja, Vizantijski Bulevar 8, Nish 18000, Serbia
[5] Univ Kragujevac, Fac Med Sci, Dept Clin & Expt Surg, Svetozara Markovica 69, Kragujevac 34000, Serbia
[6] Eye Clin, Clin Ctr Vojvodina, Hajduk Veljkova 1-9, Novi Sad 21000, Serbia
[7] Univ Med & Farm Timisoara, Dept Ophthalmol, Piata Eftimie Murgu 2, Timisoara 300041, Romania
来源
MEDICINA-LITHUANIA | 2023年 / 59卷 / 03期
关键词
OCTA; macula; vessel density; perfusion; myopia; foveal avascular zone (FAZ); OPTICAL COHERENCE TOMOGRAPHY; GANGLION-CELL COMPLEX; RETINAL MICROVASCULATURE; AXIAL LENGTH; THICKNESS; EYES; ANGIOGRAPHY; PREVALENCE; CHILDREN; VOLUME;
D O I
10.3390/medicina59030452
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and Objectives: Myopia is the most common refractive eye anomaly with a prevalence that is constantly increasing. High myopia is associated with numerous complications that can lead to permanent vision loss. It is believed that the basis of these complications lies in changes in the microvasculature of the retina caused by an increase in the longitudinal axis of the eye. Materials and Methods: Optical coherence tomography angiography (OCTA) was used to analyze differences in macular zone vascular and perfusion density and foveal avascular zone (FAZ) parameters in myopic subjects. The following OCTA parameters were analyzed: the vessel and perfusion density of retinal blood vessels in the superficial plexus; the area, perimeter, and index of circularity of the foveal avascular zone (FAZ); and foveal and ganglion cell complex (GCC) thickness. Results: Subjects with low myopia did not show statistically significant differences compared to the control for any of the analyzed parameters. Groups with moderate and high myopia showed a significant decrease in vessel and perfusion density in the parafoveal and the entire 3 x 3 mm analyzed field. Foveal vessel and perfusion densities in the myopic groups were similar to those of the control regardless of the degree of myopia. The area and perimeter of the FAZ, as well as foveal and mean GCC thickness, did not differ significantly no matter the degree of myopia, while the index of circularity was lower in highly myopic subjects. The minimal thickness of the GCC was also lower in the high myopia group. Conclusions: High and moderate myopia led to a loss of blood vessels in the macular region. Perfusion and vascular densities were preserved in the foveal region and were not affected by different degrees of myopia. The FAZ was not significantly larger in myopic subjects, but its circularity was lower in subjects with high myopia.
引用
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页数:10
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