Atrial fibrillation and stroke

被引：48

作者：

Choi, Sylvia E. ^{[1
,2
,3
]}

Sagris, Dimitrios ^{[1
,2
,4
]}

Hill, Andrew ^{[1
,2
,5
]}

Lip, Gregory Y. H. ^{[1
,2
,3
,6
]}

Abdul-Rahim, Azmil H. ^{[1
,2
,3
,5
]}

机构：

[1] Univ Liverpool, Liverpool John Moores Univ, Liverpool Ctr Cardiovasc Sci, Liverpool, England

[2] Liverpool Heart & Chest Hosp, Liverpool, England

[3] Univ Liverpool, Inst Life Course & Med Sci, Dept Cardiovasc & Metab Med, Liverpool, England

[4] Univ Thessaly, Fac Med, Sch Hlth Sci, Dept Internal Med, Larisa, Greece

[5] St Helens & Knowsley Teaching Hosp NHS Trust, Whiston Hosp, Dept Med Older People, Stroke Div, Rainhill, England

[6] Aalborg Univ, Dept Clin Med, Aalborg, Denmark

来源：

EXPERT REVIEW OF CARDIOVASCULAR THERAPY | 2023年 / 21卷 / 01期

关键词：

atrial fibrillation; cryptogenic stroke; embolic stroke; integrated care approach; oral anticoagulation; rhythm control; stroke prevention; MEAN PLATELET VOLUME; VON-WILLEBRAND-FACTOR; TRANSIENT ISCHEMIC ATTACK; SPONTANEOUS ECHO CONTRAST; ANTAGONIST ORAL ANTICOAGULANTS; HIGH-RATE EPISODES; D-DIMER LEVELS; ACUTE CARDIOEMBOLIC STROKE; HEART RHYTHM SOCIETY; HIGH-RISK PATIENTS;

D O I：

10.1080/14779072.2023.2160319

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

IntroductionStroke is one of the leading causes of mortality and morbidity globally. Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is set to reach epidemic proportions. AF is associated with a five-fold increase in risk of stroke. Strokes caused by AF more often are fatal or result in severe disability. Even though the incidence of stroke has been significantly reduced by oral anticoagulation, AF is thought to account for a significant proportion of cryptogenic strokes where no etiology is identified.Areas coveredThis article reviews the literature related to AF and stroke, pathophysiological insights, diagnosis of AF in stroke patients, and its management (Graphical Abstract).Expert opinionThe pathophysiology of thrombogenesis that links AF and stroke is not well understood and is an area of active research to identify new therapeutic targets to prevent AF and stroke. As the nature of AF and stroke is multifaceted, an integrated care approach to managing AF and stroke is increasingly essential.

引用

页码：35 / 56

页数：22

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