Atrial fibrillation and stroke

被引：48

作者：

Choi, Sylvia E. ^{[1
,2
,3
]}

Sagris, Dimitrios ^{[1
,2
,4
]}

Hill, Andrew ^{[1
,2
,5
]}

Lip, Gregory Y. H. ^{[1
,2
,3
,6
]}

Abdul-Rahim, Azmil H. ^{[1
,2
,3
,5
]}

机构：

[1] Univ Liverpool, Liverpool John Moores Univ, Liverpool Ctr Cardiovasc Sci, Liverpool, England

[2] Liverpool Heart & Chest Hosp, Liverpool, England

[3] Univ Liverpool, Inst Life Course & Med Sci, Dept Cardiovasc & Metab Med, Liverpool, England

[4] Univ Thessaly, Fac Med, Sch Hlth Sci, Dept Internal Med, Larisa, Greece

[5] St Helens & Knowsley Teaching Hosp NHS Trust, Whiston Hosp, Dept Med Older People, Stroke Div, Rainhill, England

[6] Aalborg Univ, Dept Clin Med, Aalborg, Denmark

来源：

EXPERT REVIEW OF CARDIOVASCULAR THERAPY | 2023年 / 21卷 / 01期

关键词：

atrial fibrillation; cryptogenic stroke; embolic stroke; integrated care approach; oral anticoagulation; rhythm control; stroke prevention; MEAN PLATELET VOLUME; VON-WILLEBRAND-FACTOR; TRANSIENT ISCHEMIC ATTACK; SPONTANEOUS ECHO CONTRAST; ANTAGONIST ORAL ANTICOAGULANTS; HIGH-RATE EPISODES; D-DIMER LEVELS; ACUTE CARDIOEMBOLIC STROKE; HEART RHYTHM SOCIETY; HIGH-RISK PATIENTS;

D O I：

10.1080/14779072.2023.2160319

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

IntroductionStroke is one of the leading causes of mortality and morbidity globally. Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is set to reach epidemic proportions. AF is associated with a five-fold increase in risk of stroke. Strokes caused by AF more often are fatal or result in severe disability. Even though the incidence of stroke has been significantly reduced by oral anticoagulation, AF is thought to account for a significant proportion of cryptogenic strokes where no etiology is identified.Areas coveredThis article reviews the literature related to AF and stroke, pathophysiological insights, diagnosis of AF in stroke patients, and its management (Graphical Abstract).Expert opinionThe pathophysiology of thrombogenesis that links AF and stroke is not well understood and is an area of active research to identify new therapeutic targets to prevent AF and stroke. As the nature of AF and stroke is multifaceted, an integrated care approach to managing AF and stroke is increasingly essential.

引用

页码：35 / 56

页数：22

共 287 条

[1] Association of improved outcome in acute ischaemic stroke patients with atrial fibrillation who receive early antithrombotic therapy: analysis from VISTA [J].

Abdul-Rahim, A. H. ;

Fulton, R. L. ;

Frank, B. ;

Tatlisumak, T. ;

Paciaroni, M. ;

Caso, V. ;

Diener, H. -C. ;

Lees, K. R. .

EUROPEAN JOURNAL OF NEUROLOGY, 2015, 22 (07) :1048-1055

[2] Associations with anticoagulation: a cross-sectional registry-based analysis of stroke survivors with atrial fibrillation [J].

Abdul-Rahim, Azmil H. ;

Wong, Jao ;

McAlpine, Christine ;

Young, Camilla ;

Quinn, Terence J. .

HEART, 2014, 100 (07) :557-562

[3]

Akar Joseph G, 2015, JACC Clin Electrophysiol, V1, P218, DOI 10.1016/j.jacep.2015.05.003

[4] Association of Atrial Fibrosis Quantified Using LGE-MRI with Atrial Appendage Thrombus and Spontaneous Contrast on Transesophageal Echocardiography in Patients with Atrial Fibrillation [J].

Akoum, Nazem ;

Fernandez, Genaro ;

Wilson, Brent ;

Mcgann, Christopher ;

Kholmovski, Eugene ;

Marrouche, Nassir .

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2013, 24 (10) :1104-1109

[5] Effectiveness and Safety of Non-vitamin K Antagonist Oral Anticoagulants for Atrial Fibrillation and Venous Thromboembolism: A Systematic Review and Meta-analyses [J].

Almutairi, Abdulaali R. ;

Zhou, Lili ;

Gellad, Walid F. ;

Lee, Jeannie K. ;

Slack, Marion K. ;

Martin, Jennifer R. ;

Lo-Ciganic, Wei-Hsuan .

CLINICAL THERAPEUTICS, 2017, 39 (07) :1456-1478

[6] Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE-AF Consortium [J].

Alonso, Alvaro ;

Krijthe, Bouwe P. ;

Aspelund, Thor ;

Stepas, Katherine A. ;

Pencina, Michael J. ;

Moser, Carlee B. ;

Sinner, Moritz F. ;

Sotoodehnia, Nona ;

Fontes, Joao D. ;

Janssens, A. Cecile J. W. ;

Kronmal, Richard A. ;

Magnani, Jared W. ;

Witteman, Jacqueline C. ;

Chamberlain, Alanna M. ;

Lubitz, Steven A. ;

Schnabel, Renate B. ;

Agarwal, Sunil K. ;

McManus, David D. ;

Ellinor, Patrick T. ;

Larson, Martin G. ;

Burke, Gregory L. ;

Launer, Lenore J. ;

Hofman, Albert ;

Levy, Daniel ;

Gottdiener, John S. ;

Kaeaeb, Stefan ;

Couper, David ;

Harris, Tamara B. ;

Soliman, Elsayed Z. ;

Stricker, Bruno H. C. ;

Gudnason, Vilmundur ;

Heckbert, Susan R. ;

Benjamin, Emelia J. .

JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2013, 2 (02) :e000102

[7] Is von Willebrand factor associated with stroke and death at mid-term in patients with non-valvular atrial fibrillation? [J].

Ancedy, Yann ;

Berthelot, Emmanuelle ;

Lang, Sylvie ;

Ederhy, Stephane ;

Boyer-Chatenet, Louise ;

Di Angelantonio, Emanuele ;

Soulat-Dufour, Laurie ;

Etienney, Arnaud ;

Adavane-Scheuble, Saroumadi ;

Boccara, Franck ;

Cohen, Ariel .

ARCHIVES OF CARDIOVASCULAR DISEASES, 2018, 111 (05) :357-369

[8]

ANDERSON DC, 1992, ANN INTERN MED, V116, P6

[9] Non-vitamin K antagonist oral anticoagulants in atrial fibrillation patients with chronic kidney disease: A systematic review and network meta-analysis [J].

Ando, Giuseppe ;

Capranzano, Piera .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2017, 231 :162-169

[10] Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation [J].

Andrade, Jason G. ;

Wells, George A. ;

Deyell, Marc W. ;

Bennett, Matthew ;

Essebag, Vidal ;

Champagne, Jean ;

Roux, Jean-Francois ;

Yung, Derek ;

Skanes, Allan ;

Khaykin, Yaariv ;

Morillo, Carlos ;

Jolly, Umjeet ;

Novak, Paul ;

Lockwood, Evan ;

Amit, Guy ;

Angaran, Paul ;

Sapp, John ;

Wardell, Stephan ;

Lauck, Sandra ;

Macle, Laurent ;

Verma, Atul .

NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (04) :305-315

← 1 2 3 4 5 6 7 8 9 10 →