Multi-staged vs Single-staged Pelvic Osteotomy in the Modern Treatment of Cloacal Exstrophy: Bridging the Gap

被引:3
作者
Haffar, Ahmad [1 ]
Hirsch, Alexander M. [1 ]
Crigger, Chad B. [1 ]
Harris, Thomas G. W. [1 ]
Haney, Nora M. [1 ]
Galansky, Logan B. [1 ]
Nasr, Isam W. [2 ]
Sponseller, Paul D. [3 ]
Gearhart, John P. [1 ,4 ]
机构
[1] Johns Hopkins Univ, Charlotte Bloomberg Childrens Hosp, James Buchanan Brady Urol Inst, Douglas A Canning MD Exstrophy Database Ctr,Sch Me, Baltimore, MD USA
[2] Johns Hopkins Univ, Dept Surg, Sch Med, Baltimore, MD USA
[3] Johns Hopkins Univ Hosp, Johns Hopkins Med Inst, Div Pediat Orthoped, Baltimore, MD USA
[4] Johns Hopkins Univ, James Buchanan Brady Urol Inst, Charlotte Bloomberg Childrens Ctr, Robert D Jeffs Div Pediat Urol ,Sch Med, 1800 Orleans St,Suite 7304, Baltimore, MD 21287 USA
关键词
Cloacal exstrophy; Osteotomy; Surgical complications; CLOSURE; BLADDER; COMPLICATIONS; EXPERIENCE;
D O I
10.1016/j.jpedsurg.2023.09.003
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Purpose: Staged pelvic osteotomy has been shown in the past to be an effective tool in the closure of the extreme pubic diastasis of cloacal exstrophy. The authors sought to compare orthopedic complications between non-staged pelvic osteotomies and staged pelvic osteotomies in cloacal exstrophy.Methods: A prospectively maintained exstrophy-epispadias complex database of 1510 patients was reviewed for cloacal exstrophy bladder closure events performed with osteotomy at the authors' institution. Bladder closure failure was defined as any fascial dehiscence, bladder prolapse, or vesicocutaneous fistula within one year of closure. There was a total of 172 cloacal exstrophy and cloacal exstrophy variant patients within the database and only closures at the authors' institution were included.Results: 64 closure events fitting the inclusion criteria were identified in 61 unique patients. Staged osteotomy was performed in 42 closure events and non-staged in 22 closures. Complications occurred in 46/64 closure events, with 16 grade III/IV complications. There were no associations between staged osteotomy and overall complication or grade III/IV complications (p = 0.6344 and p = 0.1286, respectively). Of the 46 total complications, 12 were orthopedic complications with 6 complications being grade III/IV. Staged osteotomy closure events experienced 10/42 orthopedic complications while non-staged osteotomy closures experienced 2/22 orthopedic complications, however this did not reach significance (p = 0.1519). Of the 64 closure events, 57 resulted in successful closure with 6 failures and one closure with planned cystectomy.Conclusion: This study confirms, in a larger series, superior outcomes when using staged pelvic osteotomy in cloacal exstrophy bladder closure. Staged osteotomy was shown to be a safe alternative to non-staged osteotomy that can decrease the risk of closure failure in this group. Staged pelvic osteotomy should be considered in all patients undergoing cloacal exstrophy bladder closure. Type of Study: Treatment study.Level of Evidence: Level III.(c) 2023 Elsevier Inc. All rights reserved.
引用
收藏
页码:2308 / 2312
页数:5
相关论文
共 18 条
[1]  
AADALEN RJ, 1980, CLIN ORTHOP RELAT R, P193
[3]  
Dindo D, 2004, ANN SURG, V240, P205, DOI [10.17116/hirurgia2018090162, 10.1097/01.sla.0000133083.54934.ae]
[4]   ANTERIOR PELVIC OSTEOTOMY - A NEW OPERATIVE TECHNIQUE FACILITATING PRIMARY BLADDER EXSTROPHY CLOSURE [J].
FREY, P ;
COHEN, SJ .
BRITISH JOURNAL OF UROLOGY, 1989, 64 (06) :641-643
[5]  
Gearhart JP, 2021, Campbell-Walsh-Wein Urology, P528
[6]   Pelvic osteotomy in cloacal exstrophy: A changing perspective [J].
Haney, Nora M. ;
Crigger, Chad B. ;
Sholklapper, Tamir ;
Mudalegundi, Shwetha ;
Griggs-Demmin, Angelica ;
Nasr, Isam W. ;
Sponseller, Paul ;
Gearhart, John P. .
JOURNAL OF PEDIATRIC SURGERY, 2023, 58 (03) :478-483
[7]   Safety and efficacy of staged pelvic osteotomies in the modern treatment of cloacal exstrophy [J].
Inouye, Brian M. ;
Tourchi, Ali ;
Di Carlo, Heather N. ;
Young, Ezekiel E. ;
Mhlanga, Joyce ;
Ko, Joan S. ;
Sponseller, Paul D. ;
Gearhart, John P. .
JOURNAL OF PEDIATRIC UROLOGY, 2014, 10 (06) :1244-1248
[8]   The dual-staged pathway for closure in cloacal exstrophy: Successful evolution in collaborative surgical practice [J].
Jayman, John ;
Michaud, Jason ;
Maruf, Mahir ;
Trock, Bruce J. ;
Kasprenski, Matthew ;
Sponseller, Paul ;
Gearhart, John .
JOURNAL OF PEDIATRIC SURGERY, 2019, 54 (09) :1761-1765
[9]   Predictors of a successful primary bladder closure in cloacal exstrophy: A multivariable analysis [J].
Jayman, John ;
Tourchi, Ali ;
Feng, Zhaoyong ;
Trock, Bruce J. ;
Maruf, Mahir ;
Benz, Karl ;
Kasprenski, Matthew ;
Baumgartner, Timothy ;
Friedlander, Daniel ;
Sponseller, Paul ;
Gearhart, John .
JOURNAL OF PEDIATRIC SURGERY, 2019, 54 (03) :491-494
[10]   A Single-Institutional Experience With Prenatal Diagnosis of Cloacal Exstrophy: Room for Improvement [J].
Morrill, Christian C. ;
Haffar, Ahmad ;
Crigger, Chad ;
Black, Mara ;
Jelin, Angie ;
Nasr, Isam ;
Gearhart, John P. .
JOURNAL OF PEDIATRIC SURGERY, 2023, 58 (10) :1949-1953