Recommendations for the Clinical Approach to Immune Thrombocytopenia: Spanish ITP Working Group (GEPTI)

被引:15
作者
Mingot-Castellano, Maria Eva [1 ]
Canaro Hirnyk, Mariana [2 ]
Sanchez-Gonzalez, Blanca [3 ]
Alvarez-Roman, Maria Teresa [4 ]
Barez-Garcia, Abelardo [5 ]
Bernardo-Gutierrez, Angel [6 ]
Bernat-Pablo, Silvia [7 ]
Bolanos-Calderon, Estefania [8 ]
Butta-Coll, Nora [9 ]
Caballero-Navarro, Gonzalo [10 ]
Caparros-Miranda, Isabel Socorro [11 ]
Entrena-Urena, Laura [12 ]
Fernandez-Fuertes, Luis Fernando [13 ]
Garcia-Frade, Luis Javier [14 ]
Gomez del Castillo, Maria del Carmen [15 ]
Gonzalez-Lopez, Tomas Jose [16 ]
Grande-Garcia, Carlos [17 ]
Guinea de Castro, Jose Maria [18 ]
Jarque-Ramos, Isidro [19 ]
Jimenez-Barcenas, Reyes [20 ]
Lopez-Ansoar, Elsa [21 ]
Martinez-Carballeira, Daniel [6 ]
Martinez-Robles, Violeta [22 ]
Monteagudo-Montesinos, Emilio [23 ]
Paramo-Fernandez, Jose Antonio [24 ]
Perera-alvarez, Maria del Mar [25 ]
Soto-Ortega, Inmaculada [6 ]
Valcarcel-Ferreiras, David [26 ]
Pascual-Izquierdo, Cristina [27 ,28 ]
机构
[1] Hosp Univ Virgen Rocio, Inst Biomed Sevilla, Dept Hematol, Seville 41013, Spain
[2] Hosp Son Espases, Dept Hematol, Palma De Mallorca 07210, Palma, Spain
[3] Hosp Mar, Dept Hematol, Barcelona 08003, Spain
[4] Univ Autonoma Madrid, Hosp Univ La Paz IdiPAZ, Dept Hematol, Madrid 28046, Spain
[5] Hosp Avila, Dept Hematol, Avila 05004, Spain
[6] Hosp Cent Asturias, Dept Hematol, Oviedo 33011, Spain
[7] Hosp Univ Plana, Dept Hematol, Villarreal 12540, Spain
[8] Hosp Clin San Carlos, Dept Hematol, IML, IdISSC, Madrid 28040, Spain
[9] Inst Investigac Hosp Univ La Paz IdiPAZ, Dept Hematol, Madrid 28046, Spain
[10] Hosp Univ Miguel Servet, Dept Hematol, Zaragoza 50009, Spain
[11] Hosp Univ Virgen Victoria, Dept Hematol, Malaga 29010, Spain
[12] Hosp Univ Virgen Nieves, Dept Hematol, Granada 18014, Spain
[13] Complejo Hosp Univ Insular Materno Infant, Dept Hematol, Las Palmas Gran Canaria 35016, Spain
[14] Hosp Univ Rio Hortega, Dept Hematol, Gerencia Reg Salud Castilla & Leon, Valladolid 47012, Spain
[15] Hosp Gen Coruna, Dept Hematol, La Coruna 15006, Spain
[16] Hosp Univ Burgos, Dept Hematol, Burgos 09006, Spain
[17] Univ Navarra Clin, Dept Hematol, Madrid 28022, Spain
[18] Hosp Univ Araba, Dept Hematol, Vitoria 01009, Spain
[19] Hosp Univ Politecn Le Fe, Dept Hematol, Valencia 46026, Spain
[20] Hosp Serrania Ronda, Dept Hematol, Ronda 29400, Spain
[21] Complejo Hosp Univ Vigo, Dept Hematol, Vigo 36312, Spain
[22] Complejo Asistencial Univ Leon, Dept Hematol, Leon 24008, Spain
[23] Hosp Univ Politecn Le Fe, Dept Pediat, Valencia 46026, Spain
[24] Univ Navarra Clin, Dept Hematol, Pamplona 31008, Spain
[25] Hosp Univ Gran Canaria Doctor Negrin, Dept Hematol, Las Palmas Gran Canaria 35010, Spain
[26] Univ Autonoma Barcelona, Vall dHebron Inst Oncol VHIO, Dept Hematol, Barcelona 08035, Spain
[27] Hosp Gen Univ Gregorio Maranon HGUGM Madrid, Inst Invest Gregorio Maranon, Dept Hematol, Madrid 28007, Spain
[28] Spanish Immune Thrombocytopenia Grp, Madrid 28040, Spain
关键词
primary immune thrombocytopenia; glucocorticoids; intravenous immunoglobulins; fostamatinib; rituximab; recommendations; THROMBOPOIETIN-RECEPTOR AGONISTS; HIGH-DOSE DEXAMETHASONE; LONG-TERM; PYLORI INFECTION; SINGLE-CENTER; FOLLOW-UP; RITUXIMAB; ELTROMBOPAG; MANAGEMENT; EFFICACY;
D O I
10.3390/jcm12206422
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diagnosis and management. In 2021, the Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated a consensus document that had been launched in 2011. The updated guidelines have been the reference for the diagnosis and management of primary ITP in Spain ever since. Nevertheless, the emergence of new tools and strategies makes it advisable to review them again. For this reason, we have updated the main recommendations appropriately. Our aim is to provide a practical tool to facilitate the integral management of all aspects of primary ITP management.
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页数:29
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