Recommendations for the Clinical Approach to Immune Thrombocytopenia: Spanish ITP Working Group (GEPTI)

被引：14

作者：

Mingot-Castellano, Maria Eva ^{[1
]}

Canaro Hirnyk, Mariana ^{[2
]}

Sanchez-Gonzalez, Blanca ^{[3
]}

Alvarez-Roman, Maria Teresa ^{[4
]}

Barez-Garcia, Abelardo ^{[5
]}

Bernardo-Gutierrez, Angel ^{[6
]}

Bernat-Pablo, Silvia ^{[7
]}

Bolanos-Calderon, Estefania ^{[8
]}

Butta-Coll, Nora ^{[9
]}

Caballero-Navarro, Gonzalo ^{[10
]}

Caparros-Miranda, Isabel Socorro ^{[11
]}

Entrena-Urena, Laura ^{[12
]}

Fernandez-Fuertes, Luis Fernando ^{[13
]}

Garcia-Frade, Luis Javier ^{[14
]}

Gomez del Castillo, Maria del Carmen ^{[15
]}

Gonzalez-Lopez, Tomas Jose ^{[16
]}

Grande-Garcia, Carlos ^{[17
]}

Guinea de Castro, Jose Maria ^{[18
]}

Jarque-Ramos, Isidro ^{[19
]}

Jimenez-Barcenas, Reyes ^{[20
]}

Lopez-Ansoar, Elsa ^{[21
]}

Martinez-Carballeira, Daniel ^{[6
]}

Martinez-Robles, Violeta ^{[22
]}

Monteagudo-Montesinos, Emilio ^{[23
]}

Paramo-Fernandez, Jose Antonio ^{[24
]}

Perera-alvarez, Maria del Mar ^{[25
]}

Soto-Ortega, Inmaculada ^{[6
]}

Valcarcel-Ferreiras, David ^{[26
]}

Pascual-Izquierdo, Cristina ^{[27
,28
]}

机构：

[1] Hosp Univ Virgen Rocio, Inst Biomed Sevilla, Dept Hematol, Seville 41013, Spain

[2] Hosp Son Espases, Dept Hematol, Palma De Mallorca 07210, Palma, Spain

[3] Hosp Mar, Dept Hematol, Barcelona 08003, Spain

[4] Univ Autonoma Madrid, Hosp Univ La Paz IdiPAZ, Dept Hematol, Madrid 28046, Spain

[5] Hosp Avila, Dept Hematol, Avila 05004, Spain

[6] Hosp Cent Asturias, Dept Hematol, Oviedo 33011, Spain

[7] Hosp Univ Plana, Dept Hematol, Villarreal 12540, Spain

[8] Hosp Clin San Carlos, Dept Hematol, IML, IdISSC, Madrid 28040, Spain

[9] Inst Investigac Hosp Univ La Paz IdiPAZ, Dept Hematol, Madrid 28046, Spain

[10] Hosp Univ Miguel Servet, Dept Hematol, Zaragoza 50009, Spain

[11] Hosp Univ Virgen Victoria, Dept Hematol, Malaga 29010, Spain

[12] Hosp Univ Virgen Nieves, Dept Hematol, Granada 18014, Spain

[13] Complejo Hosp Univ Insular Materno Infant, Dept Hematol, Las Palmas Gran Canaria 35016, Spain

[14] Hosp Univ Rio Hortega, Dept Hematol, Gerencia Reg Salud Castilla & Leon, Valladolid 47012, Spain

[15] Hosp Gen Coruna, Dept Hematol, La Coruna 15006, Spain

[16] Hosp Univ Burgos, Dept Hematol, Burgos 09006, Spain

[17] Univ Navarra Clin, Dept Hematol, Madrid 28022, Spain

[18] Hosp Univ Araba, Dept Hematol, Vitoria 01009, Spain

[19] Hosp Univ Politecn Le Fe, Dept Hematol, Valencia 46026, Spain

[20] Hosp Serrania Ronda, Dept Hematol, Ronda 29400, Spain

[21] Complejo Hosp Univ Vigo, Dept Hematol, Vigo 36312, Spain

[22] Complejo Asistencial Univ Leon, Dept Hematol, Leon 24008, Spain

[23] Hosp Univ Politecn Le Fe, Dept Pediat, Valencia 46026, Spain

[24] Univ Navarra Clin, Dept Hematol, Pamplona 31008, Spain

[25] Hosp Univ Gran Canaria Doctor Negrin, Dept Hematol, Las Palmas Gran Canaria 35010, Spain

[26] Univ Autonoma Barcelona, Vall dHebron Inst Oncol VHIO, Dept Hematol, Barcelona 08035, Spain

[27] Hosp Gen Univ Gregorio Maranon HGUGM Madrid, Inst Invest Gregorio Maranon, Dept Hematol, Madrid 28007, Spain

[28] Spanish Immune Thrombocytopenia Grp, Madrid 28040, Spain

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 20期

关键词：

primary immune thrombocytopenia; glucocorticoids; intravenous immunoglobulins; fostamatinib; rituximab; recommendations; THROMBOPOIETIN-RECEPTOR AGONISTS; HIGH-DOSE DEXAMETHASONE; LONG-TERM; PYLORI INFECTION; SINGLE-CENTER; FOLLOW-UP; RITUXIMAB; ELTROMBOPAG; MANAGEMENT; EFFICACY;

D O I：

10.3390/jcm12206422

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diagnosis and management. In 2021, the Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated a consensus document that had been launched in 2011. The updated guidelines have been the reference for the diagnosis and management of primary ITP in Spain ever since. Nevertheless, the emergence of new tools and strategies makes it advisable to review them again. For this reason, we have updated the main recommendations appropriately. Our aim is to provide a practical tool to facilitate the integral management of all aspects of primary ITP management.

引用

页数：29

共 138 条

[1] Current Advance in Thrombopoietin Receptor Agonists in the Management of Thrombocytopenia Associated With Chronic Liver Disease: Focus on Avatrombopag
Abdela, Jemal
[J]. CLINICAL MEDICINE INSIGHTS-BLOOD DISORDERS, 2019, 12
[2] Optimal use of thrombopoietin receptor agonists in immune thrombocytopenia
Al-Samkari, Hanny
Kuter, David J.
[J]. THERAPEUTIC ADVANCES IN HEMATOLOGY, 2019, 10 : 1 - 13
[3] Procoagulant profile in patients with immune thrombocytopenia
Alvarez-Roman, Maria T.
Fernandez-Bello, Ihosvany
Jimenez-Yuste, Victor
Martin-Salces, Monica
Arias-Salgado, Elena G.
Rivas Pollmar, Maria I.
Justo Sanz, Raul
Butta, Nora V.
[J]. BRITISH JOURNAL OF HAEMATOLOGY, 2016, 175 (05) : 925 - 934
[4] [Anonymous], Platelets on the Web Drug-Induced Thrombocytopenia
[5] Pathogenesis of heparin-induced thrombocytopenia
Arepally, Gowthami M.
Cines, Douglas B.
[J]. TRANSLATIONAL RESEARCH, 2020, 225 : 131 - 140
[6] Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry
Arnold, Donald M.
Nazy, Ishac
Clare, Rumi
Jaffer, Anushka M.
Aubie, Brandon
Li, Na
Kelton, John G.
[J]. BLOOD ADVANCES, 2017, 1 (25) : 2414 - 2420
[7] Platelet count response to H. pylori treatment in patients with immune thrombocytopenic purpura with and without H. pylori infection: a systematic review
Arnold, Donald M.
Bernotas, Ashley
Nazi, Ishac
Stasi, Roberto
Kuwana, Masataka
Liu, Yang
Kelton, John G.
Crowther, Mark A.
[J]. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 (06): : 850 - 856
[8] Bahadoram Mohammad, 2022, Infez Med, V30, P41, DOI 10.53854/liim-3001-5
[9] Safety of the BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting
Barda, Noam
Dagan, Noa
Ben-Shlomo, Yatir
Kepten, Eldad
Waxman, Jacob
Ohana, Reut
Hernan, Miguel A.
Lipsitch, Marc
Kohane, Isaac
Netzer, Doron
Reis, Ben Y.
Balicer, Ran D.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (12) : 1078 - 1090
[10] Thrombocytopenia and Therapeutic Strategies after Allogeneic Hematopoietic Stem Cell Transplantation
Bento, Leyre
Canaro, Mariana
Bastida, Jose Maria
Sampol, Antonia
[J]. JOURNAL OF CLINICAL MEDICINE, 2022, 11 (05)

← 1 2 3 4 5 6 7 8 9 10 →