Radiation-induced cerebral cavernous malformation: is it just a childhood disease?

被引：0

作者：

Dallo Gallo, Bruno Henrique ^{[1
]}

Galdino Chaves, Jennyfer Paulla ^{[2
]}

Gomes da Silva, Larissa Luvison ^{[3
]}

Francisco, Alexandre Novicki ^{[2
]}

Demartini Junior, Zeferino ^{[2
]}

Maeda, Adriano Keijiro ^{[2
]}

Mattozo, Carlos Alberto ^{[2
]}

机构：

[1] Pontificia Univ Catolica Parana, Curitiba, Parana, Brazil

[2] Hosp Univ Cajuru, Curitiba, Parana, Brazil

[3] CITOPAR, Pathol Dept, Curitiba, Parana, Brazil

来源：

BRITISH JOURNAL OF NEUROSURGERY | 2023年 / 37卷 / 05期

关键词：

Radiation therapy; cavernous angioma; haemorrhage; neuronavigation;

D O I：

10.1080/02688697.2020.1859092

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Cerebral cavernous malformations (CCM) are clusters of dilated sinusoidal channels, lined by a single layer of endothelium. Acquired form of these lesions was related to previous radiation-therapy, and might be related to its pathophysiology, because the vascular endothelial growth factor has higher expression in the immature brain of the child. Consequently, although it occurs mainly in the paediatric population, it can happen in adults. We report a case of radiation-induced CCM in an adult patient presenting with aggressive behaviour and cerebral haemorrhage.

引用

页码：1297 / 1300

页数：4

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