Associations of Fatty Acid Profile with Abdominal Obesity in Men

被引：2
作者：
Shramko, V. S. [1 ]
Shcherbakova, L. V. [1 ]
Kashtanova, E. V. [1 ]
Stakhneva, E. M. [1 ]
Polonskaya, Ya. V. [1 ]
Ragino, Yu. I. [1 ]
机构：
[1] Russian Acad Sci, Res Inst Internal & Prevent Med, Fed Res Ctr Inst Cytol & Genet, Siberian Branch,Siberian Div, Novosibirsk, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2023年 / 175卷 / 5期
基金：
俄罗斯科学基金会;
关键词：
abdominal obesity; body mass index; blood; fatty acids; DISEASE; RISK;
D O I：
10.1007/s10517-023-05915-x
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The content of individual unsaturated fatty acids in blood plasma (measured by HPLC) and their association with abdominal obesity in a group of men (mean age 52.2 years) was analyzed. The abdominal obesity was diagnosed according to the criteria of the All-Russian Scientific Society of Cardiology (waist circumference >94 cm). Men with abdominal obesity had higher levels of omega-6 gamma-linolenic and dihomo-gamma-linolenic acids, as well as omega-3 eicosapentaenoic and docosahexaenoic acids. They also had significantly elevated plasma levels of triglycerides and glucose and lower levels of HDL. Using single-factor ROC analysis we determined optimal cut-off thresholds for fatty acid levels indicating the presence of abdominal obesity. The results of regression analysis showed that the level of gamma-linolenic acid is directly associated with the chance of abdominal obesity.
引用
收藏
页码：629 / 632
页数：4
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