Acute Kidney Injury in Liver Cirrhosis

被引:8
作者
Attieh, Rose Mary [1 ]
Wadei, Hani M. [1 ]
机构
[1] Mayo Clin, Dept Transplant, Div Kidney & Pancreas Transplant, Jacksonville, FL 32224 USA
关键词
hepatorenal syndrome; TERLIPRESSIN PLUS ALBUMIN; SPONTANEOUS BACTERIAL PERITONITIS; INTRAHEPATIC PORTOSYSTEMIC SHUNT; GELATINASE-ASSOCIATED LIPOCALIN; RENAL REPLACEMENT THERAPY; SERUM CYSTATIN-C; HEPATORENAL-SYNDROME; INTRAVENOUS ALBUMIN; IMPROVES SURVIVAL; POOLED ANALYSIS;
D O I
10.3390/diagnostics13142361
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute kidney injury (AKI) is common in cirrhotic patients affecting almost 20% of these patients. While multiple etiologies can lead to AKI, pre-renal azotemia seems to be the most common cause of AKI. Irrespective of the cause, AKI is associated with worse survival with the poorest outcomes observed in those with hepatorenal syndrome (HRS) and acute tubular necrosis (ATN). In recent years, new definitions, and classifications of AKI in cirrhosis have emerged. More knowledge has also become available regarding the benefits and drawbacks of albumin and terlipressin use in these patients. Diagnostic tools such as urinary biomarkers and point-of-care ultrasound (POCUS) became available and they will be used in the near future to differentiate between different causes of AKI and direct management of AKI in these patients. In this update, we will review these new classifications, treatment recommendations, and diagnostic tools for AKI in cirrhotic patients.
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页数:18
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