High-flow nasal cannula improves hypoxemia in dogs failing conventional oxygen therapy

被引:9
作者
Frischer, Robert [1 ]
Daly, Jennifer [1 ]
Haggerty, Jamie [2 ]
Guenther, Christine [2 ]
机构
[1] MedVet New Orleans, Metairie, LA 70001 USA
[2] Pittsburgh Vet Specialty & Emergency Ctr, Pittsburgh, PA USA
来源
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION | 2023年 / 261卷 / 02期
关键词
POSITIVE AIRWAY PRESSURE; VENTILATION; PATIENT; IMPACT; CATS; CPAP;
D O I
10.2460/javma.22.09.0400
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
OBJECTIVE A prospective clinical trial was performed to evaluate the efficacy and tolerance of high-flow nasal cannula (HFNC) in dogs with hypoxemia. ANIMALS 20 client-owned dogs failing conventional oxygen therapy (COT). PROCEDURES Patients admitted to the ICU for treatment of hypoxemic respiratory failure were enrolled in the study. PaO2, SPO2, respiratory rate (RR), and acute patient physiologic and laboratory evaluation scores were obtained at the time of COT failure and after initiation of HFNC. Complications and patient tolerance while receiving HFNC were also recorded. RESULTS Compared to COT, the median PaO2 and SO2 were significantly higher when dogs were receiving HFNC (60.8 vs 135.6 mm Hg and 90.7% vs 99.25%, respectively). Dogs receiving HFNC had a significant reduction in median RR as compared to dogs undergoing COT (52 vs 36 breaths per minute). After the initiation of HFNC, all dogs showed clinical improvement as measured by PaO2, SO2, and RR. Of 20 dogs, 6 ultimately failed HFNC and mechanical ventilation was recommended. Nine dogs undergoing HFNC survived to discharge, and acute patient physiologic and laboratory evaluation scores had a significant positive severity correlation with death. Complications included pneumothorax in 1 dog. CLINICAL RELEVANCE COT has limited flow rates due to airway irritation caused by room temperature, nonhumidified oxygen. HFNC uses vapor humidification and heated oxygen, allowing for higher flow rates. In people, HFNC is used as escalation of oxygen therapy when COT fails. Dogs treated with HFNC had significant improvements in PaO2, SO2, and RR as compared to COT. HFNC is well tolerated and effective in treating hypoxemia in dogs.
引用
收藏
页码:210 / 216
页数:7
相关论文
共 50 条
[1]   Continuous positive airway pressure administered via face mask in tranquilized dogs [J].
Briganti, Angela ;
Melanie, Pierre ;
Portela, Diego ;
Breghi, Gloria ;
Mama, Khursheed .
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 2010, 20 (05) :503-508
[2]   Noninvasive ventilation in cats [J].
Brown, Judy E. ;
Bersenas, Alexa M. E. ;
Mathews, Karol A. ;
Kerr, Carolyn L. .
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 2009, 19 (05) :416-425
[3]   A retrospective study of positive pressure ventilation in 58 dogs: indications, prognostic factors and outcome [J].
Bruchim, Y. ;
Aroch, I. ;
Sisso, A. ;
Kushnir, Y. ;
Epstein, A. ;
Kelmer, E. ;
Segev, G. .
JOURNAL OF SMALL ANIMAL PRACTICE, 2014, 55 (06) :314-319
[4]  
Camps-Palau MA, 1999, COMP CONT EDUC PRACT, V21, P587
[5]   Evaluation of PaO2/FiO2 and SaO2/FiO2 ratios in postoperative dogs recovering on room air or nasal oxygen insufflation [J].
Carver, Andy ;
Bragg, Ryan ;
Sullivan, Lauren .
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 2016, 26 (03) :437-445
[6]   Steam burn on nose by heated, humidified high-flow nasal cannula in neonate [J].
Choi, Hwanjun ;
Lee, Junho ;
Song, Junhwan .
INTERNATIONAL WOUND JOURNAL, 2016, 13 (05) :1087-1088
[7]   Evaluation of oxygen administration with a high-flow nasal cannula to clinically normal dogs [J].
Daly, Jennifer L. ;
Guenther, Christine L. ;
Haggerty, Jamie M. ;
Keir, Iain .
AMERICAN JOURNAL OF VETERINARY RESEARCH, 2017, 78 (05) :624-630
[8]  
Drobatz KJ, 1995, KIRKS CURRENT VET TH, V12th, P175
[9]   Comparison of unilateral versus bilateral nasal catheters for oxygen administration in dogs [J].
Dunphy, ED ;
Mann, FA ;
Dodam, JR ;
Branson, KR ;
Wagner-Mann, CC ;
Johnson, PA ;
Brady, MA .
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 2002, 12 (04) :245-251
[10]   Research in high flow therapy: Mechanisms of action [J].
Dysart, Kevin ;
Miller, Thomas L. ;
Wolfson, Maria R. ;
Shaffer, Thomas H. .
RESPIRATORY MEDICINE, 2009, 103 (10) :1400-1405