Diabetes and SARS-CoV-2 Infection: The Potential Role of Antidiabetic Therapy in the Evolution of COVID-19

被引:1
作者
Pinchera, Biagio [1 ]
Schiano Moriello, Nicola [1 ]
Buonomo, Antonio Riccardo [1 ]
Di Filippo, Isabella [1 ]
Tanzillo, Anastasia [1 ]
Buzzo, Giorgio [1 ]
Villari, Riccardo [1 ]
Gentile, Ivan [1 ]
机构
[1] Univ Naples Federico II, Dept Clin Med & Surg, Sect Infect Dis, I-80131 Naples, Italy
关键词
COVID-19; SARS-CoV-2; diabetes; insulin; metformin; mTOR; METFORMIN; MECHANISMS;
D O I
10.3390/microorganisms11010145
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Diabetes mellitus represents one of the most frequent comorbidities among patients with COVID-19, constituting a risk factor for a more severe prognosis than that of non-diabetic patients. However, the pathophysiological mechanism underlying this unfavorable outcome is still not completely clear. The goal of our study was to evaluate the potential role of antidiabetic therapy in the evolution of COVID-19.
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页数:9
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