Long-term survival of patients with intracranial metastases from thyroid cancer presenting with seizures: a case report and literature review

被引:3
作者
Meng, Jiahao
Yan, Zeya
Cheng, Wei
Wang, Zilan
Chen, Zhouqing
You, Wanchun [1 ,2 ]
Wang, Zhong [1 ,2 ]
机构
[1] Soochow Univ, Affiliated Hosp 1, Dept Neurosurg & Brain, 188 Shizi St, Suzhou 215006, Peoples R China
[2] Soochow Univ, Affiliated Hosp 1, Brain & Nerve Res Lab, 188 Shizi St, Suzhou 215006, Peoples R China
关键词
Intracranial metastasis; thyroid cancer; seizure; case report; WELL-DIFFERENTIATED CARCINOMA; BRAIN METASTASES; CLINICAL CHARACTERISTICS; MANAGEMENT; PROGNOSIS; PAPILLARY;
D O I
10.21037/tcr-22-1942
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Thyroid cancer has low incidence and mortality. While metastatic cancer is the most common type of intracranial cancer, patients with intracranial metastases from thyroid cancer very rarely present with seizures. Here, we describe a case study and review the neurological symptoms and histopathology of intracranial metastases from thyroid cancer.Case Description: A 38-year-old woman was diagnosed with intracranial metastases from papillary thyroid cancer, with the chief symptom being generalized seizures. The bilateral frontal masses were completely resected in 2 operations, after which the patient was treated with whole-brain radiotherapy and tyrosine kinase inhibitors (TKIs). It has now been over 13 years since thyroid cancer resection and 51 months since she was diagnosed with intracranial metastases from papillary thyroid cancer. The long-term survival might be due to the effective and prompt treatment. Through literature review, we found the incidence of intracranial metastases from different subtypes of thyroid cancer to be inconsistent with epidemiological findings in thyroid cancer.Conclusions: Intracranial metastases of thyroid cancer should be considered when the patient has a history of thyroid cancer with seizures. A combination of surgery, radiation therapy, and TKI drugs may prolong survival.
引用
收藏
页码:439 / 446
页数:8
相关论文
共 24 条
  • [1] MANAGEMENT OF INTRACRANIAL METASTASES OF DIFFERENTIATED CARCINOMA OF THYROID
    BISWAL, BM
    BAL, CS
    SANDHU, MS
    PADHY, AK
    RATH, GK
    [J]. JOURNAL OF NEURO-ONCOLOGY, 1994, 22 (01) : 77 - 81
  • [2] Well-differentiated carcinoma of the thyroid
    Boone, RT
    Fan, CY
    Hanna, EY
    [J]. OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA, 2003, 36 (01) : 73 - +
  • [3] Prognosis and treatment of brain metastases in thyroid carcinoma
    Chiu, AC
    Delpassand, ES
    Sherman, SI
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1997, 82 (11) : 3637 - 3642
  • [4] The Largest Known Survival Analysis of Patients with Brain Metastasis from Thyroid Cancer Based on Prognostic Groups
    Choi, Jinhyun
    Kim, Jun Won
    Keum, Yo Sup
    Lee, Ik Jae
    [J]. PLOS ONE, 2016, 11 (04):
  • [5] Brain Metastases from Thyroid Carcinoma: A Retrospective Study of 21 Patients
    de Figueiredo, Benedicte Henriques
    Godbert, Yann
    Soubeyran, Isabelle
    Carrat, Xavier
    Lagarde, Philippe
    Cazeau, Anne-Laure
    Italiano, Antoine
    Sargos, Paul
    Kantor, Guy
    Loiseau, Hugues
    Bonichon, Francoise
    [J]. THYROID, 2014, 24 (02) : 270 - 276
  • [6] Brain Metastases From Differentiated Thyroid Carcinoma: Prevalence, Current Therapies, and Outcomes
    Gomes-Lima, Cristiane J.
    Wu, Di
    Rao, Sarika N.
    Punukollu, Sree
    Hritani, Rama
    Zeymo, Alexander
    Deeb, Hala
    Mete, Mihriye
    Aulisi, Edward F.
    Van Nostrand, Douglas
    Jonklaas, Jacqueline
    Wartofsky, Leonard
    Burman, Kenneth D.
    [J]. JOURNAL OF THE ENDOCRINE SOCIETY, 2019, 3 (02) : 359 - 371
  • [7] Approach to the Thyroid Cancer Patient with Extracervical Metastases
    Haugen, Bryan R.
    Kane, Madeleine A.
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (03) : 987 - 993
  • [8] Outcomes and prognostic factors in thyroid cancer patients with cranial metastases: A retrospective cohort study of 4,683 patients
    Hong, Yi-Wen
    Lin, Jen-Der
    Yu, Ming-Chin
    Hsu, Chih-Chieh
    Lin, Yann-Sheng
    [J]. INTERNATIONAL JOURNAL OF SURGERY, 2018, 55 : 182 - 187
  • [9] Influence of Epilepsy on the Quality of Life of Patients with Brain Tumors
    Krajewski, Stanislaw
    Wojcik, Magdalena
    Harat, Marek
    Furtak, Jacek
    [J]. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 18 (12)
  • [10] Clinical characteristics and follow-up of intracranial metastases from thyroid cancer
    Lee, Heui Seung
    Yoo, Heon
    Lee, Seung Hoon
    Gwak, Ho Shin
    Shin, Sang Hoon
    [J]. ACTA NEUROCHIRURGICA, 2015, 157 (12) : 2185 - 2194