Towards precision pain medicine for pain after cancer: the Cancer Pain Phenotyping Network multidisciplinary international guidelines for pain phenotyping using nociplastic pain criteria

被引：0

作者：

Nijs, Jo ^{[1
,2
,4
]}

Lahousse, Astrid ^{[1
,2
,3
,14
]}

Fontaine-de-las-Penas, Cesar ^{[12
]}

Madeleine, Pascal ^{[17
]}

Fontaine, Christel ^{[5
,9
]}

Nishigami, Tomohiko ^{[19
]}

Desmedt, Christine

Vanhoeij, Marian ^{[7
,8
]}

Mostaqim, Kenza ^{[1
]}

Cuesta-Vargas, Antonio I. ^{[11
]}

Kapreli, Eleni ^{[16
]}

Bilika, Paraskevi ^{[16
]}

Polli, Andrea ^{[1
,3
,10
]}

Leysen, Laurence ^{[1
]}

Elma, Omer ^{[1
]}

Roose, Eva ^{[1
,14
,15
]}

Rheel, Emma ^{[1
,13
]}

Yilmaz, Sevilay Tumkaya ^{[1
]}

De Baets, Liesbet ^{[1
]}

Huyamans, Eva ^{[1
,2
,3
]}

Turk, Ali ^{[18
]}

Saracoglu, Ismail ^{[6
]}

机构：

[1] Vrije Univ Brussel, Fac Phys Educ & Physiotherapy, Dept Physiotherapy Human Physiol & Anat, Pain Mot Res Grp PAIN, Brussels, Belgium

[2] Univ Hosp Brussels, Dept Phys Med & Physiotherapy, Chron Pain Rehabil, Brussels, Belgium

[3] Res Fdn Flanders FWO, Brussels, Belgium

[4] Univ Gothenburg, Inst Neurosci & Physiol, Sahlgrenska Acad, Dept Hlth & Rehabil,Unit Physiotherapy, Gothenburg, Sweden

[5] Univ Hosp Brussels, Med Oncol Dept, Brussels, Belgium

[6] Kutahya Hlth Sci Univ, Kutahya, Turkiye

[7] Univ Hosp Brussels, Breast Clin, Brussels, Belgium

[8] Vrije Univ Brussel & Pharm, Fac Med, Brussels, Belgium

[9] Katholieke Univ Leuven, Leuven, Belgium

[10] Katholieke Univ Leuven, Ctr Environm & Hlth, Dept Publ Hlth & Primary Care, Lab Clin Epigenet, Leuven, Belgium

[11] Univ Malaga, Catedra Fisioterapia, Andalucia Tech, Inst Invest Biomed Malaga IBIMA Grp Clinimetria F, Malaga, Spain

[12] Univ Rey Juan Carlos URJC, Dept Phys Therapy Occupat Therapy Phys Med & Reha, Madrid, Spain

[13] Univ Ghent, Dept Expt Clin & Hlth Psychol, Ghent, Belgium

[14] Vrije Univ Brussel, Fac Phys Educ & Physiotherapy KIMA, Rehabil Res RERE Res Grp, Dept Human Physiol & Anat, B-1090 Brussels, Belgium

[15] Univ Hasselt, REVAL, Agoralaan Gebouw A, B-3590 Diepenbeek, Belgium

[16] Univ Thessaly, Fac Hlth Sci, Physiotherapy Dept, Clin Exercise Physiol & Rehabil Res Lab, Lamia, Greece

[17] Aalborg Univ, Dept Hlth Sci & Technol, Sport Sci Performance & Technol, Aalborg, Denmark

[18] Kutahya Hlth Sci Univ, Fac Med, Dept Radiat Oncol, Kutahya, Turkiye

[19] Prefectural Univ Hiroshima, Hiroshima, Japan

来源：

BRITISH JOURNAL OF ANAESTHESIA | 2023年 / 130卷 / 05期

关键词：

cancer pain; central sensitisation; guidelines; neuropathic pain; nociceptive pain; nociplastic pain; oncology; precision medicine; QUALITY-OF-LIFE; CENTRAL SENSITIZATION INVENTORY; AXILLARY WEB SYNDROME; NEUROPATHIC PAIN; PERSISTENT PAIN; GRADING SYSTEM; POSTMASTECTOMY PAIN; CLINICAL-PRACTICE; SURGERY; HYPERSENSITIVITY;

D O I：

暂无

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Pain after cancer remains underestimated and undertreated. Precision medicine is a recent concept that refers to the ability to classify patients into subgroups that differ in their susceptibility to, biology, or prognosis of a particular disease, or in their response to a specific treatment, and thus to tailor treatment to the individual patient characteristics. Applying this to pain after cancer, the ability to classify post-cancer pain into the three major pain phenotypes (i.e. nociceptive, neuropathic, and nociplastic pain) and tailor pain treatment accordingly, is an emerging issue. This is especially relevant because available evidence suggests that nociplastic pain is present in an important subgroup of those patients experiencing post-cancer pain. The 2021 International Association for the Study of Pain (IASP) clinical criteria and grading system for nociplastic pain account for the need to identify and correctly classify patients according to the pain phenotype early in their treatment. These criteria are an important step towards precision pain medicine with great potential for the field of clinical oncology. Within this framework, the Cancer Pain Phenotyping (CANPPHE) Network, an international and interdisciplinary group of oncology clinicians and researchers from seven countries, applied the 2021 IASP clinical criteria for nociplastic pain to the growing population of those experiencing post-cancer pain. A manual is provided to allow clinicians to differentiate between predominant nociceptive, neuropathic, or nociplastic pain after cancer. A seven-step diagnostic approach is presented and illustrated using cases to enhance understanding and encourage effective implementation of this approach in clinical practice.

引用

页码：611 / 621

页数：11