The article examines the history of the activity of the Academic Center under the Kyrgyz (Kazakh) People's Commissariat of Education (1921-1926). In studying this topic, one should take into account the works in which the activities of public organizations, their members, and the contribution of the intelligentsia to the study of the region are studied. For example, there are not a few scientific papers devoted to the activities of the Society for the Study of Kazakhstan, but in this case the specific object of research is an Academic Center. And the work of this public organization was considered one of the many activities of the Academic Center. Therefore, this study is supposed to reveal in more detail the diverse aspects of the activities of the Academic Center. Historical sources were obtained from the funds of the Central State Archive of the Republic of Kazakhstan, the United State Orenburg Regional Archive of the Russian Federation. These materials reveal the diverse activities of the Academic Center. The Academic Center stood at the origins of the formation and development of archives, museums, publishing, secular education, scientific and educational activities at the state level. It contributed to the eradication of illiteracy. The Academic Center was one of the main institutions where the Kazakh intelligentsia was most united. The Academic Center in its research activities relied on a number of scientific organizations, such as the Society for the Study of Kazakhstan, the Scientific and Pedagogical Society and the Physical and Mathematical Society, Science and Labor, the Orenburg branch of the Russian Geographical Society.