Transarterial chemoembolization for liver metastases of a pancreatic neuroendocrine neoplasm: a single-center experience

被引：1

作者：

Nanno, Yoshihide ^{[1
]}

Toyama, Hirochika ^{[1
]}

Ueshima, Eisuke ^{[2
]}

Sofue, Keitaro ^{[2
]}

Matsumoto, Ippei ^{[3
]}

Ishida, Jun ^{[1
]}

Urade, Takeshi ^{[1
]}

Fukushima, Kenji ^{[1
]}

Gon, Hidetoshi ^{[1
]}

Tsugawa, Daisuke ^{[1
]}

Komatsu, Shohei ^{[1
]}

Kuramitsu, Kaori ^{[1
]}

Goto, Tadahiro ^{[1
]}

Asari, Sadaki ^{[1
]}

Yanagimoto, Hiroaki ^{[1
]}

Kido, Masahiro ^{[1
]}

Ajiki, Tetsuo ^{[1
]}

Fukumoto, Takumi ^{[1
]}

机构：

[1] Kobe Univ Grad, Dept Surg, Div Hepatobiliary Pancreat Surg, Sch Med, 7-5-2 Kusunoki Cho,Chuo Ku, Kobe 6500017, Japan

[2] Kobe Univ, Dept Radiol, Grad Sch Med, Kobe, Japan

[3] Kindai Univ, Fac Med, Dept Surg, Div Hepatobiliary Pancreat Surg, Osaka, Japan

来源：

SURGERY TODAY | 2023年 / 53卷 / 12期

关键词：

Liver metastasis; Pancreatic neuroendocrine tumor; Transarterial chemoembolization; ABSCESS FORMATION; TUMORS; MANAGEMENT; EVEROLIMUS; MIDGUT;

D O I：

10.1007/s00595-023-02714-9

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Transarterial chemoembolization (TACE) is performed for pancreatic neuroendocrine tumor (PanNEN) liver metastases; however, the safety and efficacy of TACE procedures, especially for patients who have undergone previous pancreatic surgery, have not been established. We reviewed 48 TACE procedures (1-6 procedures/patient) performed on 11 patients with PanNEN liver metastases, including 16 TACE procedures (4-6 procedures/patient) for 3 patients with a history of biliary-enteric anastomosis. The overall tumor objective response rate was 94%. The incidence of Clavien-Dindo grade & GE; 2 complications was 1/16 (6%) and 1/32 (3%), and the median time to untreatable progression was 31 (14-41) and 27 (2-60) months among patients with and without a history of biliary-enteric anastomosis, respectively. Although validation is needed in future studies, our experiences have shown that TACE treatment is a viable treatment option for PanNEN liver metastases, even after biliary-enteric anastomosis with experienced teams and careful patient follow-up.

引用

页码：1396 / 1400

页数：5

共 21 条

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