Pseudo-Meigs' syndrome secondary to breast cancer with ovarian metastasis: a case report and literature review

被引:2
作者
Lin, Xiang-Ying [1 ]
Zhou, Xiao-Jun [2 ]
Yang, Shi-Ping [1 ]
Zheng, Jia-Xuan [3 ]
Li, Zhao-Jun [1 ]
机构
[1] Hainan Med Univ, Hainan Gen Hosp, Dept Radiat Oncol, Hainan Affiliated Hosp, Haikou, Peoples R China
[2] Hainan Med Univ, Hainan Gen Hosp, Dept Clin Lab, Hainan Affiliated Hosp, Haikou, Peoples R China
[3] Hainan Med Univ, Hainan Gen Hosp, Dept Pathol, Hainan Affiliated Hosp, Haikou, Peoples R China
基金
中国国家自然科学基金;
关键词
breast cancer; Pseudo-Meigs' syndrome; ovarian metastasis; endocrine therapy; oophorectomy; TUMORS;
D O I
10.3389/fonc.2023.1091956
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Ovarian metastasis of breast cancer with pseudo-Meigs' syndrome (PMS) is extremely rare. Only four cases of PMS secondary to breast cancer with ovarian metastasis have been reported to date. In this report, we present the fifth case of PMS caused by ovarian metastasis of breast cancer. On the 2nd of July 2019, a 53-year-old woman presented to our hospital with complaints of abdominal distension, irregular vaginal bleeding, and chest distress. Color Doppler ultrasound examination revealed a mass approximately 109x89 mm in size in the right adnexal area, accompanied by multiple uterine fibroids and a large amount of pelvic and peritoneal effusions. The patient had no common symptoms and showed no signs of breast cancer. The main manifestations were a right ovarian mass, massive hydrothorax, and ascites. Lab workup and imaging revealed raised CA125 (cancer antigen 125) levels and multiple bone metastases. At first the patient was misdiagnosed with ovarian carcinoma. After the rapid disappearance of oophorectomy hydrothorax and ascites, and decreased CA125 levels, from 1,831.8u/ml to normal range. According to the pathology report, breast cancer was finally diagnosed. The patient underwent endocrine therapy (Fulvestrant) and azole treatment after oophorectomy. At the 40-month follow-up, the patient was still alive and doing well.
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页数:6
相关论文
共 22 条
[1]   The role of inflammatory cytokines in Meigs' syndrome [J].
Abramov, Y ;
Anteby, SO ;
Fasouliotis, SJ ;
Barak, V .
OBSTETRICS AND GYNECOLOGY, 2002, 99 (05) :917-919
[2]   Ovarian metastasis from breast cancer mimicking a primary ovarian neoplasm: A case report [J].
Akizawa, Yoshika ;
Kanno, Toshiyuki ;
Horibe, Yu ;
Shimizu, Yumi ;
Noguchi, Eiichiro ;
Yamamoto, Tomoko ;
Okamoto, Takahiro ;
Nagashima, Yoji ;
Tabata, Tsutomu .
MOLECULAR AND CLINICAL ONCOLOGY, 2021, 15 (01)
[3]   Pseudo-Meigs' syndrome caused by breast cancer metastasis to both ovaries. [J].
Fujii M. ;
Okino M. ;
Fujioka K. ;
Yamashita K. ;
Hamano K. .
Breast Cancer, 2006, 13 (4) :344-348
[4]  
GAGNON Y, 1989, CANCER-AM CANCER SOC, V64, P892, DOI 10.1002/1097-0142(19890815)64:4<892::AID-CNCR2820640422>3.0.CO
[5]  
2-C
[6]  
HORVATH TJ, 1977, FORTSCHR MED, V95, P358
[7]   Pseudo-Meigs' syndrome associated with breast cancer metastasis to both ovaries: Report of a case [J].
Kawakubo, Naonori ;
Okido, Masayuki ;
Tanaka, Risa ;
Mitsugi, Kenji ;
Fukuhara, Masao ;
Aishima, Shinichi ;
Kato, Masato ;
Ichimiya, Hitoshi .
SURGERY TODAY, 2010, 40 (12) :1148-1151
[8]  
Lin JY., 1992, OBSTET GYNECOL, V80, P653, DOI [10.3109/01674829209019578, DOI 10.3109/01674829209019578]
[10]   Pseudo-Meigs' syndrome caused by secondary ovarian tumors from gastrointestinal cancer - A case report and review of the literature [J].
Nagakura, S ;
Shirai, Y ;
Hatakeyama, K .
DIGESTIVE SURGERY, 2000, 17 (04) :418-419