The future of food allergy: Challenging existing paradigms of clinical practice

被引:16
作者
Anagnostou, Aikaterini [1 ,2 ,12 ]
Lieberman, Jay [3 ]
Greenhawt, Matthew [4 ]
Mack, Douglas Paul [5 ]
Santos, Alexandra F. [6 ,7 ,8 ]
Venter, Carina [9 ]
Stukus, David [2 ,10 ]
Turner, Paul J. [11 ]
Brough, Helen A. [6 ,8 ]
机构
[1] Texas Childrens Hosp, Dept Pediat, Sect Immunol Allergy & Retrovirol, Houston, TX USA
[2] Baylor Coll Med, Sect Allergy Immunol & Retrovirol, Houston, TX USA
[3] Univ Tennessee, LeBonheur Childrens Hosp, Hlth Sci Ctr, Dept Pediat, Memphis, TN USA
[4] Univ Colorado, Childrens Hosp Colorado, Sch Med, Food Challenge & Res Unit,Dept Pediat,Sect Allergy, Denver, CO USA
[5] McMaster Univ, Dept Pediat, Hamilton, ON, Canada
[6] Kings Coll London, Fac Life Sci & Med, Sch Life Courses Sci, Dept Women & Childrens Hlth Pediatr Allergy, London, England
[7] Kings Coll London, Fac Life Sci & Med, Sch Immunol & Microbial Sci, Peter Gorer Dept Immunobiol, London, England
[8] Guys & St Thomass NHS Fdn Trust, Evelina Childrens Hosp, Childrens Allergy Serv, London, England
[9] Univ Colorado, Childrens Hosp Colorado, Dept Pediat, Sect Allergy & Immunol, Denver, CO USA
[10] Ohio State Univ, Nationwide Childrens Hosp, Coll Med, Columbus, OK USA
[11] Imperial Coll London, Natl Heart & Lung Inst, London, England
[12] Feigin Ctr, 1102 Bates Ave Suite 330,MS BCM320, Houston, TX 77030 USA
关键词
food allergy; novel diagnostics; prevention; shared decision-making; therapy; BASOPHIL ACTIVATION TEST; SHARED DECISION-MAKING; EARLY PEANUT INTRODUCTION; LIFE GUT MICROBIOME; QUALITY-OF-LIFE; ARA H 2; ORAL IMMUNOTHERAPY; COWS MILK; LONG-TERM; PREDICTION MODEL;
D O I
10.1111/all.15757
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
The field of food allergy has seen tremendous change over the past 5-10 years with seminal studies redefining our approach to prevention and management and novel testing modalities in the horizon. Early introduction of allergenic foods is now recommended, challenging the previous paradigm of restrictive avoidance. The management of food allergy has shifted from a passive avoidance approach to active interventions that aim to provide protection from accidental exposures, decrease allergic reaction severity and improve the quality of life of food-allergic patients and their families. Additionally, novel diagnostic tools are making their way into clinical practice with the goal to reduce the need for food challenges and assist physicians in the-often complex-diagnostic process. With all the new developments and available choices for diagnosis, prevention and therapy, shared decision-making has become a key part of medical consultation, enabling patients to make the right choice for them, based on their values and preferences. Communication with patients has also become more complex over time, as patients are seeking advice online and through social media, but the information found online may be outdated, incorrect, or lacking in context. The role of the allergist has evolved to embrace all the above exciting developments and provide patients with the optimal care that fits their needs. In this review, we discuss recent developments as well as the evolution of the field of food allergy in the next decade.
引用
收藏
页码:1847 / 1865
页数:19
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