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Shanghai Jiao Tong Univ, Shanghai Key Lab Tumor Microenvironm & Inflammat, Key Lab Cell Differentiat & Apoptosis, Dept Biochem & Mol Cell Biol,Minist Educ,Sch Med, Shanghai, Peoples R China Shanghai Jiao Tong Univ, Shanghai Key Lab Tumor Microenvironm & Inflammat, Key Lab Cell Differentiat & Apoptosis, Dept Biochem & Mol Cell Biol,Minist Educ,Sch Med, Shanghai, Peoples R China