Executive functioning in body dysmorphic disorder and obsessive-compulsive disorder

被引:4
作者
Chen, Long Long [1 ,2 ]
Flygare, Oskar [1 ,2 ]
Wallert, John [1 ,2 ]
Enander, Jesper [1 ,2 ]
Ivanov, Volen Z. [1 ,2 ]
Ruck, Christian [1 ,2 ]
Djurfeldt, Diana [1 ,2 ]
机构
[1] Karolinska Inst, Ctr Psychiat Res, Dept Clin Neurosci, Stockholm, Sweden
[2] Karolinska Univ Hosp, Stockholm Cty Council, Stockholm Hlth Care Serv, Huddinge, Sweden
关键词
Obsessive-compulsive disorder; body dysmorphic disorder; executive functions; cognition; neuropsychiatry; FRONTAL-LOBE DYSFUNCTION; WORKING-MEMORY; NEUROPSYCHOLOGICAL PERFORMANCE; RESPONSE-INHIBITION; COGNITIVE DEFICITS; RATING-SCALE; TESTS; ENDOPHENOTYPES; METAANALYSIS; RELIABILITY;
D O I
10.1017/S1092852921000705
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective To assess executive functions (EFs) in patients with body dysmorphic disorder (BDD) and obsessive-compulsive disorder (OCD) compared with healthy controls. Methods Adults diagnosed with BDD (n = 26) or OCD (n = 29) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, and healthy controls (n = 28) underwent validated and computerized neuropsychological tests, spatial working memory (SWM), intra-extra-dimensional set shifting (IED), and stop signal task (SST), from the Cambridge Neuropsychological Test Automated Battery (CANTAB). Test performance was compared between groups, and correlated with standardized symptom severity of BDD and OCD. Significance level was set to P < .05. Results There were no statistically significant between-group differences on key outcome measures in SWM, IED, or SST. There was a weak positive correlation between symptom severity and test errors on SWM and IED in both OCD and BDD groups; increased clinical severity was associated with more errors in these tests. Furthermore, there was a negative correlation between symptom severity and SST in the BDD group. Conclusions Patients with BDD or OCD did not differ from healthy control subjects in terms of test performance; however, there were several statistically significant correlations between symptom severity and performance in those with BDD or OCD. More studies on EFs in BDD and OCD are required to elucidate if there are differences in EFs between these two disorders.
引用
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页码:33 / 40
页数:8
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