A New Digital Point-of-Care Tool With Advanced Blood Glucose Measuring Technology

被引：4

作者：

Gessler, Simon ^{[1
]}

Porsch, Ulrich ^{[1
]}

Klonoff, David C. ^{[2
]}

Marquant, Michael ^{[1
]}

机构：

[1] Roche Diagnost GmbH, Mannheim, Germany

[2] Mills Peninsula Med Ctr, Diabet Res Inst, San Mateo, CA USA

来源：

JOURNAL OF DIABETES SCIENCE AND TECHNOLOGY | 2023年 / 17卷 / 05期

关键词：

blood glucose; detection; interference; meter; test strip;

D O I：

10.1177/19322968221092763

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

cobas((R)) pulse is a point-of-care blood glucose (BG) measuring system for multiple-patient use in professional healthcare settings. The system provides advances in connectivity and BG measuring technology, and has multiple fail-safes to improve accuracy and reduce the risk of user error. Flavin adenine dinucleotide-dependent glucose dehydrogenase on the working electrode catalyzes oxidation of ss-D-glucose in the blood sample. A redox mediator/electron acceptor, on both the working and the counter electrode, facilitates diffusion of electrons in proportion to the glucose concentration and compensates for the effects of potential interfering agents. During development, >1 million test strip measurements were performed using >8000 test scenarios to refine the algorithm model. No clinically relevant interference was identified with extreme variations in blood properties and drugs in whole blood samples.

引用

页码：1321 / 1325

页数：5