NEUROLOGICAL SOFT SIGNS AND SOCIAL COGNITION IN PATIENTS WITH SCHIZOPHRENIA: THE MISSING LINK

被引:0
作者
Guevara, Kaloyan [1 ,2 ]
Kostadinov, Kostadin [3 ]
机构
[1] Stavanger Univ Hosp, Dept Psychiat, 12 Jan Johnsens Gate, N-4011 Stavanger, Norway
[2] Med Univ Sofia, Dept Psychiat, 1St Georgi Sofiiski St, B-1431 Sofia, Bulgaria
[3] Medical Univ Plovdiv, Fac Publ Hlth, Dept Social Med & Publ Hlth, 15A Vasil Aprilov Blvd, Plovdiv 4002, Bulgaria
来源
COMPTES RENDUS DE L ACADEMIE BULGARE DES SCIENCES | 2023年 / 76卷 / 09期
关键词
schizophrenia; social cognition; neurological soft signs; NES; AKDEF; ABNORMALITIES;
D O I
10.7546/CRABS.2023.09.15
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Schizophrenia is a debilitating mental disorder characterised by a pro-nounced decline in mental, physical, and social functioning. Our study aims to investigate the relationship between the socio-cognitive and the subtle motor and sensory symptoms of schizophrenia, which are, respectively, represented by facial emotion recognition deficits (FERD) and neurological soft signs (NSS). Thus, we assessed 60 patients diagnosed with schizophrenia. FERD was mea-sured with the "Averaged Karolinska Directed Emotional Faces" set, and NSS was assessed with the Neurological Evaluation Scale. A strong and significant negative correlation was found between the NSS total score and the FERD total score (r = -0.7, p < 0.001). There was also a significant negative corre-lation between several of the subscores of both instruments. The results show that impaired social cognition is significantly associated with soft neurologi-cal disturbances in patients suffering from schizophrenia. Taken together, this reinforces the notion that schizophrenia is characterised by dysfunction and disconnection of a complex cerebral network, which can probably be influenced by psychosocial and physical nonpharmacological therapeutic interventions.
引用
收藏
页码:1440 / 1448
页数:9
相关论文
共 20 条
[1]   Neural systems for recognizing emotion [J].
Adolphs, R .
CURRENT OPINION IN NEUROBIOLOGY, 2002, 12 (02) :169-177
[2]  
Association AP, 2013, Diagnostic and statistical manual of mental disorders, V5
[3]   Significance and meaning of neurological signs in schizophrenia: Two decades later [J].
Bombin, I ;
Arango, C ;
Buchanan, RW .
SCHIZOPHRENIA BULLETIN, 2005, 31 (04) :962-977
[4]   THE NEUROLOGICAL EVALUATION SCALE (NES) - A STRUCTURED INSTRUMENT FOR THE ASSESSMENT OF NEUROLOGICAL SIGNS IN SCHIZOPHRENIA [J].
BUCHANAN, RW ;
HEINRICHS, DW .
PSYCHIATRY RESEARCH, 1989, 27 (03) :335-350
[5]   Impaired facial emotion perception in schizophrenia: A meta-analysis [J].
Chan, Raymond C. K. ;
Li, Huijie ;
Cheung, Eric F. C. ;
Gong, Qi-yong .
PSYCHIATRY RESEARCH, 2010, 178 (02) :381-390
[6]   Emotion recognition impairment is present early and is stable throughout the course of schizophrenia [J].
Comparelli, Anna ;
Corigliano, Valentina ;
De Carolis, Antonella ;
Mancinelli, Iginia ;
Trovini, Giada ;
Ottavi, Giorgia ;
Dehning, Julia ;
Tatarelli, Roberto ;
Brugnoli, Roberto ;
Girardi, Paolo .
SCHIZOPHRENIA RESEARCH, 2013, 143 (01) :65-69
[7]   Perceived emotion genuineness: normative ratings for popular facial expression stimuli and the development of perceived-as-genuine and perceived-as-fake sets [J].
Dawel, Amy ;
Wright, Luke ;
Irons, Jessica ;
Dumbleton, Rachael ;
Palermo, Romina ;
O'Kearney, Richard ;
McKone, Elinor .
BEHAVIOR RESEARCH METHODS, 2017, 49 (04) :1539-1562
[8]   Facial Emotion Recognition in Schizophrenia [J].
Gao, Zhiyun ;
Zhao, Wentao ;
Liu, Sha ;
Liu, Zhifen ;
Yang, Chengxiang ;
Xu, Yong .
FRONTIERS IN PSYCHIATRY, 2021, 12
[9]  
Girdler Steven J, 2019, Psychopharmacol Bull, V49, P56
[10]  
HEINRICHS DW, 1988, AM J PSYCHIAT, V145, P11