Aggressive Angiomyxoma of the Vulva: Which Is the Best Management Strategy? Description of a Case Report and Review of Literature of the Last Ten Years

被引:12
|
作者
Gulino, Ferdinando Antonio [1 ]
Gulisano, Marianna [1 ]
Ettore, Carla [1 ]
Giorlandino, Alexandra [2 ]
Russo, Emanuele [1 ]
Ettore, Giuseppe [1 ]
机构
[1] Azienda Rilievo Nazl & Alta Specializzaz ARNAS Gar, Dept Obstet & Gynaecol, I-95124 Catania, Italy
[2] Azienda Rilievo Nazl & Alta Specializzaz ARNAS Gar, Dept Pathol Anat, I-95124 Catania, Italy
关键词
aggressive angiomyxoma; mesenchymal tumour; genital tumour; vulvar lesion; ULTRASOUND; VAGINA; MASS;
D O I
10.3390/jcm12051726
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Aggressive angiomyxoma is a rare mesenchymal tumour of the genital tract with a high incidence in women of reproductive age. The aim of our work is to understand which is the best management strategy for this condition, starting from the description of a rare case report up to the performance of a narrative review of the literature. Methods: We report a case of a 46-year-old woman who came to our attention because of the growth of a 10-centimetre pedunculated, non-soft, non-tender mass of the left labium majus. She underwent surgical excision, and the histologic diagnosis was aggressive angiomyxoma. Due to a lack of tumour-free margins, radicalization surgery was carried out after three months. A review of the literature of the last ten years was performed following the PRISMA statement on MEDLINE (PubMed). We obtained data from twenty-five studies describing thirty-three cases. Results: Aggressive angiomyxoma is characterized by a high recurrence rate of between 36 and 72% after surgery. There is no universal consensus about hormonal therapy, and most studies (85%) describe surgical excision followed by only clinical and radiological follow-up. Conclusion: Wide surgical excision is the gold-standard treatment for aggressive angiomyxoma, succeeded by either clinical or radiological (ultrasound or MRI) follow-up.
引用
收藏
页数:11
相关论文
共 33 条
  • [1] Aggressive angiomyxoma of the vulva: a case report and review of literature
    Inge Dierickx
    Karen Deraedt
    Willy Poppe
    Jasper Verguts
    Archives of Gynecology and Obstetrics, 2008, 277 : 483 - 487
  • [2] Aggressive angiomyxoma of the vulva: a case report and review of literature
    Dierickx, Inge
    Deraedt, Karen
    Poppe, Willy
    Verguts, Jasper
    ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2008, 277 (06) : 483 - 487
  • [3] Aggressive Angiomyxoma of the Vulva: Case Report and Literature Review
    Sun, N. X.
    Li, W.
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2010, 38 (04) : 1547 - 1552
  • [4] Aggressive angiomyxoma in pregnancy: a case report and literature review
    Xu, Haihua
    Sun, Pengming
    Xu, Rongli
    Wang, Lihua
    Shi, Yuequan
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2020, 48 (07)
  • [5] Aggressive angiomyxoma of the vagina A case report and literature review
    Yu, Bo Ram
    Choi, Won Ku
    Cho, Dong Hyu
    Lee, Na-Ri
    MEDICINE, 2025, 104 (04) : e41287
  • [6] Aggressive angiomyxoma: case report and review of the literature
    Tsarpalis, D. C.
    Giannakopoulos, C. K.
    Lagadas, A. A.
    Toufexi, E. G.
    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2007, 28 (06) : 480 - 482
  • [7] Giant superficial angiomyxoma of the vulva: a case report and review of the literature
    Kim, Hyun-Soo
    Kim, Gou Young
    Lim, Sung-Jig
    Ki, Kyung-Do
    Kim, Hyun Cheol
    JOURNAL OF CUTANEOUS PATHOLOGY, 2010, 37 (06) : 672 - 677
  • [8] Aggressive angiomyxoma of pelvis: A case report and literature review
    Lin, Xue-Mei
    Wang, Li
    Wang, Qiong
    MEDICINE, 2022, 101 (46) : E31617
  • [9] Aggressive angiomyxoma of the thigh: A case report and review of the literature
    Liu, Xinying
    Li, Xinghua
    Yang, Yinlong
    ONCOLOGY LETTERS, 2012, 4 (03) : 467 - 470
  • [10] Aggressive angiomyxoma of the vagina: a case report and review of the literature
    Papachristou, DJ
    Batistatou, A
    Paraskevaidis, E
    Agnantis, NJ
    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 2004, 25 (04) : 519 - 521