Caffeic Acid and Diseases-Mechanisms of Action

被引:80
|
作者
Pavlikova, Nela [1 ,2 ]
机构
[1] Charles Univ Prague, Fac Med 3, Div Cell & Mol Biol, Prague 10000, Czech Republic
[2] Charles Univ Prague, Fac Med 3, Ctr Res Diabet Metab & Nutr, Prague 10000, Czech Republic
关键词
caffeic acid; cancer; diabetes; obesity; atherosclerosis; Alzheimer's disease; HEPATOCELLULAR-CARCINOMA; ANTICANCER ACTIVITY; ENDOTHELIAL-CELLS; CHLOROGENIC ACID; IN-VIVO; STAPHYLOCOCCUS-AUREUS; INDUCED NEUROTOXICITY; OXIDATIVE STRESS; PHENETHYL ESTER; BREAST-CANCER;
D O I
10.3390/ijms24010588
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Caffeic acid belongs to the polyphenol compounds we consume daily, often in the form of coffee. Even though it is less explored than caffeic acid phenethyl ester, it still has many positive effects on human health. Caffeic acid can affect cancer, diabetes, atherosclerosis, Alzheimer's disease, or bacterial and viral infections. This review focuses on the molecular mechanisms of how caffeic acid achieves its effects.
引用
收藏
页数:18
相关论文
共 50 条
  • [1] Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
    Alam, Manzar
    Ahmed, Sarfraz
    Elasbali, Abdelbaset Mohamed
    Adnan, Mohd
    Alam, Shoaib
    Hassan, Imtaiyaz
    Pasupuleti, Visweswara Rao
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [2] Revealing the Curative Possibilities: A Comprehensive Exploration of Caffeic Acid
    Goyal, Ahsas
    Singh, Vishwa Deep
    Solanki, Kunal
    Verma, Aanchal
    CURRENT PHARMACEUTICAL BIOTECHNOLOGY, 2024,
  • [3] Atherosclerosis in Autoimmune Rheumatic Diseases-Mechanisms and Clinical Findings
    Zinger, Hasya
    Sherer, Yaniv
    Shoenfeld, Yehuda
    CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2009, 37 (01) : 20 - 28
  • [4] Caffeic Acid on Metabolic Syndrome: A Review
    Muhammad Abdul Kadar, Nellysha Namela
    Ahmad, Fairus
    Teoh, Seong Lin
    Yahaya, Mohamad Fairuz
    MOLECULES, 2021, 26 (18):
  • [5] Caffeic acid and its derivative caffeic acid phenethyl ester as potential therapeutic compounds for cardiovascular diseases: A systematic review
    Shad, Arya Nasimi
    Akhlaghipour, Iman
    Baghan, Atefeh Babazadeh
    Askari, Vahid Reza
    Rahimi, Vafa Baradaran
    ARCHIV DER PHARMAZIE, 2024, 357 (10)
  • [6] Protective role of caffeic acid in an Aβ25-35-induced Alzheimer's disease model
    Kim, Ji Hyun
    Wang, Qian
    Choi, Ji Myung
    Lee, Sanghyun
    Cho, Eun Ju
    NUTRITION RESEARCH AND PRACTICE, 2015, 9 (05) : 480 - 488
  • [7] Protective Effects of Caffeic Acid and the Alzheimer's Brain: An Update
    Habtemariam, Solomon
    MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2017, 17 (08) : 667 - 674
  • [8] Effects of Lipoic Acid, Caffeic Acid and a Synthesized Lipoyl-Caffeic Conjugate on Human Hepatoma Cell Lines
    Guerriero, Eliana
    Sorice, Angela
    Capone, Francesca
    Costantini, Susan
    Palladino, Pasquale
    D'ischia, Marco
    Castello, Giuseppe
    MOLECULES, 2011, 16 (08): : 6365 - 6377
  • [9] The role of PCSK9 in heart failure and other cardiovascular diseases-mechanisms of action beyond its effect on LDL cholesterol
    Dutka, Mieczyslaw
    Zimmer, Karolina
    Cwiertnia, Michal
    Ilczak, Tomasz
    Bobinski, Rafal
    HEART FAILURE REVIEWS, 2024, 29 (05) : 917 - 937
  • [10] Chemical, Biological, and Pharmacological Prospects of Caffeic Acid
    Aijaz, Mohd
    Keserwani, Nishith
    Yusuf, Mohd
    Ansari, Nizamul Haque
    Ushal, Ruhinaz
    Kalia, Pankaj
    BIOINTERFACE RESEARCH IN APPLIED CHEMISTRY, 2022, 13 (04):