Treatment-emergent mutations in myelodysplastic syndrome with del(5q) - lenalidomide related or disease-intrinsic clonal evolution?

被引：1

作者：

Abdallah, Mostafa ^{[1
]}

Reichard, Kaaren ^{[1
]}

Gangat, Naseema ^{[1
]}

Tefferi, Ayalew ^{[1
]}

机构：

[1] Mayo Clin, Rochester, MN 55905 USA

来源：

BLOOD CANCER JOURNAL | 2024年 / 14卷 / 01期

关键词：

TP53; MUTATIONS; PREVALENCE;

D O I：

10.1038/s41408-024-01027-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页数：4

共 15 条

[1] International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data [J].

Arber, Daniel A. ;

Orazi, Attilio ;

Hasserjian, Robert P. ;

Borowitz, Michael J. ;

Calvo, Katherine R. ;

Kvasnicka, Hans-Michael ;

Wang, Sa A. ;

Bagg, Adam ;

Barbui, Tiziano ;

Branford, Susan ;

Bueso-Ramos, Carlos E. ;

Cortes, Jorge E. ;

Dal Cin, Paola ;

DiNardo, Courtney D. ;

Dombret, Herve ;

Duncavage, Eric J. ;

Ebert, Benjamin L. ;

Estey, Elihu H. ;

Facchetti, Fabio ;

Foucar, Kathryn ;

Gangat, Naseema ;

Gianelli, Umberto ;

Godley, Lucy A. ;

Gokbuget, Nicola ;

Gotlib, Jason ;

Hellstrom-Lindberg, Eva ;

Hobbs, Gabriela S. ;

Hoffman, Ronald ;

Jabbour, Elias J. ;

Kiladjian, Jean-Jacques ;

Larson, Richard A. ;

Le Beau, Michelle M. ;

Loh, Mignon L. -C. ;

Lowenberg, Bob ;

Macintyre, Elizabeth ;

Malcovati, Luca ;

Mullighan, Charles G. ;

Niemeyer, Charlotte ;

Odenike, Olatoyosi M. ;

Ogawa, Seishi ;

Orfao, Alberto ;

Papaemmanuil, Elli ;

Passamonti, Francesco ;

Porkka, Kimmo ;

Pui, Ching-Hon ;

Radich, Jerald P. ;

Reiter, Andreas ;

Rozman, Maria ;

Rudelius, Martina ;

Savona, Michael R. .

BLOOD, 2022, 140 (11) :1200-1228

[2] TP53 mutations and variant allele frequency in myelodysplastic syndromes with del(5q): A Mayo-Moffitt study of 156 informative cases [J].

Fleti, Farah ;

Chan, Onyee ;

Singh, Amritpal ;

Abdelmagid, Maymona G. ;

Al-Kali, Aref ;

Elliott, Michelle A. ;

Begna, Kebede H. ;

Foran, James M. ;

Badar, Talha ;

Khera, Nandita ;

Al Ali, Najla H. ;

Padron, Eric ;

Sallman, David A. ;

Shah, Mithun ;

Hiwase, Devendra ;

Pardanani, Animesh ;

Arber, Daniel A. ;

Orazi, Attilio ;

Reichard, Kaaren K. ;

He, Rong ;

Ketterling, Rhett P. ;

Gangat, Naseema ;

Komrokji, Rami ;

Tefferi, Ayalew .

AMERICAN JOURNAL OF HEMATOLOGY, 2023, 98 (04) :E76-E79

[3] Emergence of TP53 mutation during lenalidomide therapy of myelodysplastic syndrome with del(5q) and its subsequent disappearance following salvage therapy with decitabine [J].

Gangat, Naseema ;

Bellam, Naresh ;

Reichard, Kaaren ;

Tefferi, Ayalew .

HAEMATOLOGICA, 2024, 109 (04) :1306-1309

[4] Allogeneic Stem Cell Transplantation for Myelodysplastic Syndrome Patients with a 5q Deletion [J].

Garderet, Laurent ;

Ziagkos, Dimitris ;

Van Biezen, Anja ;

Lacobelli, Simona ;

Finke, Juergen ;

Maertens, Johan ;

Volin, Liisa ;

Ljungman, Per ;

Chevallier, Patrice ;

Passweg, Jakob ;

Schaap, Nicolaas ;

Beelen, Dietrich ;

Nagler, Arnon ;

Blaise, Didier ;

Poire, Xavier ;

Yakoub-Agha, Ibrahim ;

Lenhoff, Stig ;

Craddock, Charles ;

Schots, Rik ;

Rambaldi, Alessandro ;

Sanz, Jaime ;

Jindra, Pavel ;

Mufti, Ghulam J. ;

Robin, Marie ;

Kroeger, Nicolaus .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2018, 24 (03) :507-513

[5] Myelodysplastic syndromes with del(5q): A real-life study of determinants of long-term outcomes and response to lenalidomide [J].

Gurnari, Carmelo ;

Piciocchi, Alfonso ;

Soddu, Stefano ;

Bonanni, Fabrizio ;

Scalzulli, Emilia ;

Niscola, Pasquale ;

Di Veroli, Ambra ;

Piccioni, Anna Lina ;

Piedimonte, Monica ;

Maiorana, Gianluca ;

Salutari, Prassede ;

Cicconi, Laura ;

Santopietro, Michelina ;

Gumenyuk, Svitlana ;

Sarlo, Chiara ;

Fenu, Susanna ;

Tafuri, Agostino ;

Latagliata, Roberto ;

Fianchi, Luana ;

Criscuolo, Marianna ;

Maciejewski, Jaroslaw P. ;

Maurillo, Luca ;

Buccisano, Francesco ;

Breccia, Massimo ;

Voso, Maria Teresa .

BLOOD CANCER JOURNAL, 2022, 12 (09)

[6] Clonal heterogeneity in the 5q-syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression [J].

Jadersten, Martin ;

Saft, Leonie ;

Pellagatti, Andrea ;

Goehring, Gudrun ;

Wainscoat, James S. ;

Boultwood, Jacqueline ;

Porwit, Anna ;

Schlegelberger, Brigitte ;

Hellstrom-Lindberg, Eva .

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 (12) :1762-1766

[7] TP53 Mutations in Low-Risk Myelodysplastic Syndromes With del(5q) Predict Disease Progression [J].

Jaedersten, Martin ;

Saft, Leonie ;

Smith, Alexander ;

Kulasekararaj, Austin ;

Pomplun, Sabine ;

Goehring, Gudrun ;

Hedlund, Anette ;

Hast, Robert ;

Schlegelberger, Brigitte ;

Porwit, Anna ;

Hellstrom-Lindberg, Eva ;

Mufti, Ghulam J. .

JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15) :1971-1979

[8] Efficacy of lenalidomide in myelodysplastic syndromes [J].

List, A ;

Kurtin, S ;

Roe, DJ ;

Buresh, A ;

Mahadevan, D ;

Fuchs, D ;

Rimsza, L ;

Heaton, R ;

Knight, R ;

Zeldis, JB .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (06) :549-557

[9] Emergence and evolution of TP53 mutations are key features of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide [J].

Lode, Laurence ;

Menard, Audrey ;

Flet, Laurent ;

Richebourg, Steven ;

Loirat, Marion ;

Eveillard, Marion ;

Le Bris, Yannick ;

Godon, Catherine ;

Theisen, Olivier ;

Gagez, Anne-Laure ;

Cartron, Guillaume ;

Commes-Maerten, Therese ;

Villemagne, Bruno ;

Luycx, Odile ;

Godmer, Pascal ;

Pellat-Deceunynck, Catherine ;

Soussi, Thierry ;

Bene, Marie C. ;

Delaunay, Jacques ;

Peterlin, Pierre .

HAEMATOLOGICA, 2018, 103 (04) :E143-E146

[10] Prevalence, clonal dynamics and clinical impact of TP53 mutations in patients with myelodysplastic syndrome with isolated deletion (5q) treated with lenalidomide: results from a prospective multicenter study of the german MDS study group (GMDS) [J].

Mossner, M. ;

Jann, J-C ;

Nowak, D. ;

Platzbecker, U. ;

Giagounidis, A. ;

Goetze, K. ;

Letsch, A. ;

Haase, D. ;

Shirneshan, K. ;

Braulke, F. ;

Schlenk, R. F. ;

Haferlach, T. ;

Schafhausen, P. ;

Bug, G. ;

Luebbert, M. ;

Ganser, A. ;

Buesche, G. ;

Schuler, E. ;

Nowak, V. ;

Pressler, J. ;

Oblaender, J. ;

Fey, S. ;

Mueller, N. ;

Lauinger-Loersch, E. ;

Metzgeroth, G. ;

Weiss, C. ;

Hofmann, W-K ;

Germing, U. ;

Nolte, F. .

LEUKEMIA, 2016, 30 (09) :1956-1959

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