Aptamers: Features, Synthesis and Applications

被引:15
作者
Aiswarya, P. U. [1 ]
Raj, Gopika [1 ]
John, Jinju [1 ]
Mohan, K. Malavika [1 ]
John, Franklin [1 ]
George, Jinu [1 ]
机构
[1] Sacred Heart Coll, Dept Chem, Bioorgan Lab, Kochi 682013, India
关键词
aptamers; SELEX; sensors; therapeutics; targeted drug delivery; diagnosis; NUCLEIC-ACID APTAMERS; DNA APTAMERS; DRUG-DELIVERY; CANCER-CELLS; RNA APTAMER; APTASENSORS; SELECTION; PROTEIN; AGGREGATION; DIAGNOSTICS;
D O I
10.1002/cbdv.202301008
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Aptamers have become a topic of interest among the researchers and scientists since they not only possess all of the benefits of antibodies but also possess special qualities including heat stability, low cost, and limitless uses. Here we give a review about the features, applications, and challenges of aptamers and also how they are beneficial over the antibodies for biomedical applications. Their unique features make aptamers a prominent tool in therapeutics, diagnostics, biosensors and targeted drug delivery. In conclusion, aptamers represent exciting materials for a variety of applications and can be modified to improve their properties and to extend their applications in biomedical field.
引用
收藏
页数:22
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