Primary Hyperparathyroidism, Hypoparathyroidism and Vitamin D

被引：0

作者：

Cardoso, Luis ^{[1
,2
,3
]}

Ferreira, Mafalda Martins ^{[1
]}

机构：

[1] Ctr Hosp & Univ Coimbra, Serv Endocrinol, P-3004561 Coimbra, Portugal

[2] Univ Porto, Inst Invest & Inovac Saude, Porto, Portugal

[3] Univ Coimbra, Fac Med, Coimbra, Portugal

来源：

REVISTA PORTUGUESA DE ENDOCRINOLOGIA DIABETES E METABOLISMO | 2023年 / 18卷

关键词：

Calcium; Hyperparathyroidism; Hypoparathyroidism; Parathyroid Hormone; Supplementation; Vitamin D; PARATHYROID ADENOMA WEIGHT; D DEFICIENCY; D REPLETION; BONE;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The use of active vitamin D analogues in hypoparathyroidism is well established, since low levels of parathyroid hormone (PTH) reduce the activity of renal 1 alpha-hydroxylase, reducing the synthesis of 1,25-OH-vitamin D and consequently decreasing serum calcium and magnesium and increasing phosphatemia. In primary hyperparathyroidism, vitamin D deficit additionally contributes to the elevation of PTH and serum calcium and to the reduction of phosphatemia. In addition, it increases the risk of hungry bone syndrome postoperatively. Vitamin D supplementation in primary hyperparathyroidism is safe if hypercalcemia is mild (<12 mg/dL) and if calcium levels are periodically monitored, and is associated with reduced bone remodelling, the risk of hungry bone syndrome and lower postoperative PTH levels. A minimum 25OH-vitamine D of 20 ng/mL is advised in these patients.

引用

页码：57 / 59

页数：3

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