Structural highlights of macromolecular complexes and assemblies

被引：0

作者：

Vallat, Brinda ^{[1
,2
,3
]}

Berman, Helen M. ^{[1
,2
,4
,5
]}

机构：

[1] Rutgers State Univ, Res Collaboratory Struct Bioinformat Prot Data Ban, Prot Data Bank, Piscataway, NJ 08854 USA

[2] Rutgers State Univ, Piscataway, NJ 08854 USA

[3] Rutgers State Univ, Canc Inst New Jersey, New Brunswick, NJ 08901 USA

[4] Rutgers State Univ, Dept Chem & Chem Biol, Piscataway, NJ 08854 USA

[5] Univ Southern Calif, Dept Quantitat & Computat Biol, Los Angeles, CA 90089 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2024年 / 85卷

基金：

美国国家科学基金会;

关键词：

ARCHITECTURE; RELIABILITY; ACCURACY; DYNAMICS;

D O I：

10.1016/j.sbi.2023.102773

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structures of macromolecular assemblies have given us deep insights into cellular processes and have profoundly impacted biological research and drug discovery. We highlight the structures of macromolecular assemblies that have been modeled using integrative and computational methods and describe how open access to these structures from structural archives has empowered the research community. The arsenal of experimental and computational methods for structure determination ensures a future where whole organelles and cells can be modeled.

引用

页数：9

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