Mathematical and Numerical Investigations for a Cholera Dynamics With a Seasonal Environment

We propose a mathematical model for the vibrio cholerae spread under the influence of a seasonal environment with two routes of infection. We proved the existence of a unique bounded positive solution, and that the system admits a global attractor set. The basic reproduction number R0 was calculated for both cases, the fixed and seasonal environment which permits to characterise both, the extinction and the persistence of the disease. We proved that the phage-free equilibrium point is globally asymptotically stable if R-0 <= 1, while the disease will be persist if R-0 > 1. Finally, extensive numerical simulations are given to confirm the theoretical findings.