Effectiveness of Shenshu Guanxin recipe granules ((sic)) for improving exercise tolerance in patients with stable angina pectoris: a randomized, double-blind, placebo-controlled trial

被引：0
作者：
Jin, Xiao [1 ]
Wu, Bingxin [2 ]
Wu, Huanlin [3 ]
Xu, Danping [4 ]
机构：
[1] Jinan Univ, Affiliated Hosp 1, Dept Tradit Chinese Med, Guangzhou 510630, Peoples R China
[2] Guangzhou Univ Chinese Med, Clin Coll 2, Dept Cardiol, Guangzhou 510000, Peoples R China
[3] Anzhen Hosp, Dept Cardiol, Beijing 100029, Peoples R China
[4] Sun Yat sen Univ, Affiliated Hosp 8, Dept Tradit Chinese Med, Shenzhen 518033, Peoples R China
来源：
JOURNAL OF TRADITIONAL CHINESE MEDICINE | 2023年 / 43卷 / 06期
关键词：
exercise tolerance; angina; stable; Seattle Angina Questionnaire; Shenshu Guanxin recipe granules; CORONARY-HEART-DISEASE; TRADITIONAL CHINESE MEDICINE; GUIDELINES; INTERVENTION; MANAGEMENT; MECHANISM; PROTOCOL; THERAPY; HEALTH;
D O I：
10.19852/j.cnki.jtcm.20231008.001
中图分类号：
R [医药、卫生];
学科分类号：
10 ;
摘要：
OBJECTIVE: To assess the effectivess of Shenshu Guanxin recipe granules ((sic), SGR) in improving exercise tolerance and the quality of life in patients with Stable Angina Pectoris (SAP). METHODS: A total of 189 patients were consecutively enrolled between December 2012 and December 2014. The included patients were randomly assigned to SGR and placebo groups. The primary endpoints included mainly the results of treadmill exercise test and Seattle Angina Questionnaire (SAQ) during 12 weeks of treatment. RESULTS: After 12 weeks of treatment, SGR extended the time of exercise-induced ST-segment depression of 0.1 MV, lowered the maximum ST-segment depression, and shortened the duration of ST-segment depression in patients with SAP in southern China. Besides, the study also proved that SGR could improve the quality of life and functional status of patients with SAP. CONCLUSIONS: SGR showed a positive effect on exercise tolerance compared with the placebo besides optimal medical therapy. Also, the study proved that SGR could improve the SAQ score of the patients. (c) 2023 JTCM. All rights reserved.
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收藏
页码：1227 / 1233
页数：7
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