A GPU accelerated study of aqueous humor dynamics in human eyes using the lattice Boltzmann method

被引:1
作者
Huang, Gang [1 ,2 ]
Ye, Qianlin [1 ]
Tang, Hao [2 ]
Qin, Zhangrong [2 ]
机构
[1] Jiangxi Univ Sci & Technol, Business Sch, Ganzhou, Jiangxi, Peoples R China
[2] Guangxi Normal Univ, Guangxi Key Lab Multisource Informat Min & Secur, Guilin 541004, Peoples R China
基金
中国国家自然科学基金;
关键词
lattice Boltzmann method; aqueous humor dynamics; GPU; sparse matrix; NUMERICAL-SIMULATION; FLUID-DYNAMICS; HEAT-TRANSFER; MODEL; FLOW; OPTIMIZATION; CONVECTION; PRESSURE; SOLVER;
D O I
10.3934/mbe.2023372
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In this paper, we presented a 3D human eyes aqueous humor (AH) dynamics model, and additionally, designed and optimized it using GPU technology. First, the feasibility of the model is demonstrated through validation. Then, the effect of different factors on AH flow was investigated using the validated model. The experimental results showed that AH flow more rapidly when standing than supine; the intraocular temperature has the greatest effect on AH flow compared to other factors; the AH secretion rate and trabecular meshwork (TM) permeability had a greater effect on intraocular pressure (IOP). Corneal indentation and ovoid anterior chamber (AC) can also affect AH flow. Finally, the PartSparse algorithm based GPU can save more than 50% of the memory consumption and achieves a performance of 1491.29 MLUPS and a Speedup of 837.61 times.
引用
收藏
页码:8476 / 8497
页数:22
相关论文
共 34 条
[1]   Investigation of Saccadic Eye Movement Effects on the Fluid Dynamic in the Anterior Chamber [J].
Abouali, Omid ;
Modareszadeh, Amirreza ;
Ghaffarieh, Alireza ;
Tu, Jiyuan .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 2012, 134 (02)
[2]  
Astorino M., 2013, SEMA J, V59, P53, DOI DOI 10.1007/BF03322610
[3]  
Canning CR, 2002, IMA J MATH APPL MED, V19, P31
[4]   LATTICE BOLTZMANN MODEL FOR SIMULATION OF MAGNETOHYDRODYNAMICS [J].
CHEN, SY ;
CHEN, HD ;
MARTINEZ, D ;
MATTHAEUS, W .
PHYSICAL REVIEW LETTERS, 1991, 67 (27) :3776-3779
[5]   Numerical simulations of fluid pressure in the human eye [J].
Crowder, T. R. ;
Ervin, V. J. .
APPLIED MATHEMATICS AND COMPUTATION, 2013, 219 (24) :11119-11133
[6]   Numerical simulation of aqueous humor flow: From healthy to pathologic situations [J].
Ferreira, J. A. ;
de Oliveira, P. ;
da Silva, P. M. ;
Murta, J. N. .
APPLIED MATHEMATICS AND COMPUTATION, 2014, 226 :777-792
[7]   Fluid mechanics of the human eye: Aqueous humour flow in the anterior chamber [J].
Fitt, AD ;
Gonzalez, G .
BULLETIN OF MATHEMATICAL BIOLOGY, 2006, 68 (01) :53-71
[8]   A lattice Boltzmann model for convection heat transfer in porous media [J].
Guo, ZL ;
Zhao, TS .
NUMERICAL HEAT TRANSFER PART B-FUNDAMENTALS, 2005, 47 (02) :157-177
[9]   A coupled lattice BGK model for the Boussinesq equations [J].
Guo, ZL ;
Shi, BC ;
Zheng, CG .
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, 2002, 39 (04) :325-342
[10]   Non-equilibrium extrapolation method for velocity and pressure boundary conditions in the lattice Boltzmann method [J].
Guo, ZL ;
Zheng, CG ;
Shi, BC .
CHINESE PHYSICS, 2002, 11 (04) :366-374