Extraskeletal myxoid chondrosarcoma of the gingival: a rare case report and review of the literature

被引：0

作者：

Li, Jiaqi ^{[1
,2
,3
,4
]}

Zheng, Zhijian ^{[3
,4
]}

Deng, Hao ^{[1
,2
,5
]}

Men, Yi ^{[1
,2
,3
,6
]}

Chen, Yu ^{[1
,2
,3
,4
]}

Han, Qi ^{[1
,2
,3
,4
]}

机构：

[1] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, Chengdu 610041, Peoples R China

[2] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, Chengdu 610041, Peoples R China

[3] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, State Key Lab Oral Dis, Chengdu 610041, Peoples R China

[4] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, Dept Oral Pathol, Chengdu 610041, Peoples R China

[5] First Peoples Hosp Ziyang, Dept Stomatol, Ziyang 641300, Peoples R China

[6] Sichuan Univ, West China Hosp Stomatol, Natl Clin Res Ctr Oral Dis, Dept Head & Neck Oncol, Chengdu 610041, Peoples R China

来源：

DIAGNOSTIC PATHOLOGY | 2023年 / 18卷 / 01期

关键词：

Extraskeletal myxoid chondrosarcoma; Malignant tumor; Mandibular gingiva; Immunohistochemistry; Differential diagnoses; TEMPORAL BONE; ODONTOGENIC MYXOMA; CHONDROBLASTOMA; OSTEOSARCOMA;

D O I：

10.1186/s13000-023-01390-0

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

BackgroundExtraskeletal myxoid chondrosarcoma (EMC) is a rare malignant tumor described in the head and neck region, especially in the gingival. We present one case arising in the gingival of right mandible, and briefly reviewed the related literature.Case presentationA 24-year-old male patient with a lesion of 3.5*2.0 cm in buccal gingival of right posterior mandible for 2 months. The tumor was composed of cartilaginous structures and myxoid matrix. Immunohistochemical(IHC) showed that the tumor cells to be positive for vimentin, focally positive for S-100, negative for calponin, SMA, SOX10. The Ki-67 labelling index was 80%. Fluorescent in situ Hybridization (FISH) was positive for NR4A3 rearrangement.ConclusionsDue to its unusual site and low incidence in the oral region, a combination of histological findings, immunohistochemistry, and molecular pathology as well as differential diagnosis with other diseases should be taken into consideration in the process of clinical diagnosis and treatment.

引用

页数：10

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