Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection

被引:0
|
作者
Lu, Dongming [1 ]
Yaqoob, Obaid [2 ]
Kumar, Manish [3 ,4 ]
Kushwah, Ajay Singh [2 ]
Sharma, Rahul Kumar [2 ]
Kumar, Devinder [2 ]
Mavai, Yogendra [5 ]
Khan, Rukaiya [6 ]
机构
[1] Nanjing Univ, Jinling Hosp, Sch Med, Dept Pulm & Crit Care Med, Nanjing 210000, Jiangsu, Peoples R China
[2] Amar Shaheed Baba Ajit Singh Jujhar Singh Mem Coll, Bela Autonomous Coll, Dept Pharmacol, Ropar 140111, Punjab, India
[3] Chitkara Univ, Chitkara Coll Pharm, Rajpura 140401, Punjab, India
[4] Penn State Univ, Coll Med, Penn State Hlth Milton S Hershey Med Ctr, Dept Neurosurg, State Coll, PA 17033 USA
[5] IPS Coll Pharm, Shivpuri Link Rd, Gwalior 474001, Madhya Pradesh, India
[6] Abhilashi Coll Pharm, Nerchowk Mandi 175008, Himachal Prades, India
关键词
COVID-19; asthma; smoking; critical care; SARS-CoV-2; COMMUNITY-ACQUIRED PNEUMONIA; SARS CORONAVIRUS; TOBACCO USE; CIGARETTE-SMOKING; RECEPTOR; SPIKE; EXPRESSION; EXPOSURE; STEP; ACE2;
D O I
10.2478/acph-2023-0002
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This century's most serious catastrophe, COVID-19, has been dubbed "the most life-threatening disaster ever ". Asthmatic persons are even more prone to COVID-19's complex interplay with the underlying inflammatory condition. In order to protect themselves against COVID-19, asthmatic patients must be very vigilant in their usage of therapeutic techniques and drugs (e.g., bronchodilators, 5-lipoxygenase inhibitors), which may be accessed to deal with mild, moderate, and severe COVID-19 indications. People with asthma may have more severe COVID-19 symptoms, which may lead to a worsening of their condition. Several cytokines were found to be elevated in the bronchial tracts of patients with acute instances of COVID-19, suggesting that this ailment may aggravate asthma episodes by increasing inflammation. The intensity of COVID-19 symptoms is lessened in patients with asthma who have superior levels of T-cells. Several antibiotics, antivirals, antipyretics, and anti-inflammatory drugs have been suggested to suppress COVID-19 symptoms in asthmatic persons. Furthermore, smokers are more likely to have aggravated repercussions in COVID-19 infection. Being hospitalized to critical care due to COVID-19, needing mechanical breathing, and suffering from serious health repercussions, are all possible outcomes for someone who has previously smoked. Smoking damages airways and alveoli, which significantly raises the risk of COVID-19-related health complications. Patients with a previous record of smoking are predisposed to severe COVID-19 disease symptoms that essentially require a combination of bronchodilators, mucolytics, antivirals, and antimuscarinic drugs, to cope with the situation. The present review discusses the care and management of asthmatic and smoker patients in COVID-19 infection.
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页码:29 / 42
页数:14
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