Biomedical Application of Decellularized Scaffolds

被引：6

作者：

Zhang, Fang ^{[1
]}

Gao, Huimin ^{[1
]}

Jiang, Xuefeng ^{[1
]}

Yang, Fang ^{[1
]}

Zhang, Jun ^{[1
]}

Song, Saijie ^{[1
]}

Shen, Jian ^{[1
,2
]}

机构：

[1] Nanjing Normal Univ, Natl & Local Joint Engn Res Ctr Biomed Funct Mat, Sch Chem & Mat Sci, Nanjing 210023, Peoples R China

[2] Nanjing Univ, Jiangsu Engn Res Ctr Interfacial Chem, Nanjing 210023, Peoples R China

来源：

ACS APPLIED BIO MATERIALS | 2023年 / 6卷 / 12期

关键词：

polymer; biomaterials; decellularizedscaffold; tissue engineering; biomedical application; MESENCHYMAL STEM-CELLS; HUMAN AMNIOTIC MEMBRANE; EXTRACELLULAR-MATRIX; BIOLOGIC SCAFFOLD; RE-ENDOTHELIALIZATION; SURFACE MODIFICATION; NERVE ALLOGRAFTS; CROSS-LINKING; DENTAL-PULP; SKIN-GRAFT;

D O I：

10.1021/acsabm.3c00778

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Tissue loss and end-stage organ failure are serious health problems across the world. Natural and synthetic polymer scaffold material based artificial organs play an important role in the field of tissue engineering and organ regeneration, but they are not from the body and may cause side effects such as rejection. In recent years, the biomimetic decellularized scaffold based materials have drawn great attention in the tissue engineering field for their good biocompatibility, easy modification, and excellent organism adaptability. Therefore, in this review, we comprehensively summarize the application of decellularized scaffolds in tissue engineering and biomedicine in recent years. The preparation methods, modification strategies, construction of artificial tissues, and application in biomedical applications are discussed. We hope that this review will provide a useful reference for research on decellularized scaffolds and promote their application tissue engineering.

引用

页码：5145 / 5168

页数：24

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