ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age

被引:2
作者
Elena Camacho-Moll, Maria [1 ,2 ]
Ramirez-Daher, Zayra [3 ]
Leticia Escobedo-Guajardo, Brenda [1 ]
Cesar Davila-Valero, Julio [3 ]
Rodriguez-de la Garza, Brenda Ludmila [3 ]
Bermudez de Leon, Mario [1 ]
机构
[1] Mexican Social Secur Inst, Ctr Biomed Res Northeast, Dept Mol Biol, Calle 2 Abril 501, Monterrey 64720, Nuevo Leon, Mexico
[2] Univ Monterrey, Ctr Mol Diag & Personalized Med, Hlth Sci Div, Ave Ignacio Morones Prieto 4500 Pte, San Pedro Garza Garcia 66238, Nuevo Leon, Mexico
[3] Mexican Social Secur Inst, Ctr Guadalupe, Residency Geriatr, Zone Gen Hosp 4,C Mariano Matamoros 300, Guadalupe 67100, Nuevo Leon, Mexico
关键词
Admitting department; Hospital; Aged; Critical care; Geriatrics; Hospitalized; Pandemics;
D O I
10.1186/s12877-023-03864-8
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
BackgroundOne of the risk factors for getting seriously ill from COVID-19 and reaching high mortality rates is older age. Older age is also associated with comorbidities, which are risk factors for severe COVID-19 infection. Among the tools that have been evaluated to predict intensive care unit (ICU) admission and mortality is ABC-GOALScl.AimIn the present study we validated the utility of ABC-GOALScl to predict in-hospital mortality in subjects over 60 years of age who were positive for SARS-CoV-2 virus at the moment of admission with the purpose of optimizing sanitary resources and offering personalized treatment for these patients.MethodsThis was an observational, descriptive, transversal, non-interventional and retrospective study of subjects (>= 60 years of age), hospitalized due to COVID-19 infection at a general hospital in northeastern Mexico. A logistical regression model was used for data analysis.ResultsTwo hundred forty-three subjects were included in the study, whom 145 (59.7%) passed away, while 98 (40.3%) were discharged. Average age was 71, and 57.6% were male. The prediction model ABC-GOALScl included sex, body mass index, Charlson comorbidity index, dyspnea, arterial pressure, respiratory frequency, SpFi coefficient (Saturation of oxygen/Fraction of inspired oxygen ratio), serum levels of glucose, albumin, and lactate dehydrogenase; all were measured at the moment of admission. The area under the curve for the scale with respect to the variable of discharge due to death was 0.73 (IC 95% = 0.662-0.792).ConclusionThe ABC-GOALScl scale to predict ICU admission in COVID-19 patients is also useful to predict in-hospital death in COVID-19 patients >= 60 years old.
引用
收藏
页数:7
相关论文
共 26 条
[1]  
[Anonymous], 2020, WHO COVID 19 DASHB
[2]   Development and validation of a prediction model for severe respiratory failure in hospitalized patients with SARS-CoV-2 infection: a multicentre cohort study (PREDI-CO study) [J].
Bartoletti, Michele ;
Giannella, Maddalena ;
Scudeller, Luigia ;
Tedeschi, Sara ;
Rinaldi, Matteo ;
Bussini, Linda ;
Fornaro, Giacomo ;
Pascale, Renato ;
Pancaldi, Livia ;
Pasquini, Zeno ;
Trapani, Filippo ;
Badia, Lorenzo ;
Campoli, Caterina ;
Tadolini, Marina ;
Attard, Luciano ;
Puoti, Massimo ;
Merli, Marco ;
Mussini, Cristina ;
Menozzi, Marianna ;
Meschiari, Marianna ;
Codeluppi, Mauro ;
Barchiesi, Francesco ;
Cristini, Francesco ;
Saracino, Annalisa ;
Licci, Alberto ;
Rapuano, Silvia ;
Tonetti, Tommaso ;
Gaibani, Paolo ;
Ranieri, Vito M. ;
Viale, Pierluigi .
CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (11) :1545-1553
[3]   Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes [J].
Bonafe, Massimiliano ;
Prattichizzo, Francesco ;
Giuliani, Angelica ;
Storci, Gianluca ;
Sabbatinelli, Jacopo ;
Olivieri, Fabiola .
CYTOKINE & GROWTH FACTOR REVIEWS, 2020, 53 :33-37
[4]   Comparison of clinical characteristics and performance of pneumonia severity score and CURB-65 among younger adults, elderly and very old subjects [J].
Chen, Jung-Hsiang ;
Chang, Shy-Shin ;
Liu, Jason J. ;
Chan, Rai-Chi ;
Wu, Jiunn-Yih ;
Wang, Wei-Chuan ;
Lee, Si-Huei ;
Lee, Chien-Chang .
THORAX, 2010, 65 (11) :971-977
[5]   Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study [J].
Clark, Andrew ;
Jit, Mark ;
Warren-Gash, Charlotte ;
Guthrie, Bruce ;
Wang, Harry H. X. ;
Mercer, Stewart W. ;
Sanderson, Colin ;
McKee, Martin ;
Troeger, Christopher ;
Ong, Kanyin L. ;
Checchi, Francesco ;
Perel, Pablo ;
Joseph, Sarah ;
Gibbs, Hamish P. ;
Banerjee, Amitava ;
Eggo, Rosalind M. .
LANCET GLOBAL HEALTH, 2020, 8 (08) :1003-1017
[6]   Predicting In-Hospital Mortality in COVID-19 Older Patients with Specifically Developed Scores [J].
Covino, Marcello ;
De Matteis, Giuseppe ;
Burzo, Maria Livia ;
Russo, Andrea ;
Forte, Evelina ;
Carnicelli, Annamaria ;
Piccioni, Andrea ;
Simeoni, Benedetta ;
Gasbarrini, Antonio ;
Franceschi, Francesco ;
Sandroni, Claudio .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2021, 69 (01) :37-43
[7]   Novel coronavirus (COVID-19) infection: What a doctor on the frontline needs to know [J].
Down, Billy ;
Kulkarni, Sagar ;
Khan, Ameer Hamid Ahmed ;
Barker, Benjamin ;
Tang, Ivan .
ANNALS OF MEDICINE AND SURGERY, 2020, 55 :24-29
[8]   COVID-IRS: A novel predictive score for risk of invasive mechanical ventilation in patients with COVID-19 [J].
Garcia-Gordillo, Jose Antonio ;
Camiro-Zuniga, Antonio ;
Aguilar-Soto, Mercedes ;
Cuenca, Dalia ;
Cadena-Fernandez, Arturo ;
Khouri, Latife Salame ;
Rayek, Jesica Naanous ;
Mercado, Moises .
PLOS ONE, 2021, 16 (04)
[9]  
Guenther T., 2020, SSRN ELECT J, DOI [10.2139/ssrn.3654517, DOI 10.2139/SSRN.3654517]
[10]   Development and Validation of the Quick COVID-19 Severity Index: A Prognostic Tool for Early Clinical Decompensation [J].
Haimovich, Adrian D. ;
Ravindra, Neal G. ;
Stoytchev, Stoytcho ;
Young, H. Patrick ;
Wilson, Francis P. ;
van Dijk, David ;
Schulz, Wade L. ;
Taylor, R. Andrew .
ANNALS OF EMERGENCY MEDICINE, 2020, 76 (04) :442-453