Seismic resilience (SR) plays a vital role in evaluating and improving performance losses along with saving repair costs of structures from potential earthquakes. To further explore the developments, hotspots, and trend directions of SR, a total of 901 articles are obtained from the Web of Science (WoS) database. CiteSpace software is used to conduct a bibliometric analysis, which indicates an upward trend of publications in SR and explores the relationship of countries, journals, cited references, and keywords based on visual maps and detailed tables. Then, based on the results of the bibliometric analysis, a state-of-the-art review is conducted to further explore the current challenges and trend directions of SR. The trend directions can be divided into five categories: (a) SR assessments of infrastructure structures, (b) multi-hazard quantifications of SR, (c) seismic resilient structures, (d) refining and calibrating analytical models, and (e) multi-criteria decision-making frameworks for sustainability and SR.