Dispensing of antibiotics for tuberculosis patients using standardized patient approach at community pharmacies: results from a cross-sectional study in Pakistan

被引:1
作者
Gillani, Ali Hassan [1 ,2 ,3 ]
Arshad, Hafsa [1 ,2 ,3 ]
Mujtaba, Hasan [4 ]
Umer, Muhammad Farooq [5 ]
Xu, Sen [1 ,2 ,3 ]
Ji, Wenjing [1 ,2 ,3 ]
Bashir, Kamran [6 ]
Chang, Jie [1 ,2 ,3 ]
Yang, Caijun [1 ,2 ,3 ]
Fang, Yu [1 ,2 ,3 ]
机构
[1] Xi An Jiao Tong Univ, Sch Pharm, Dept Pharm Adm & Clin Pharm, Xian, Shaanxi, Peoples R China
[2] Xi An Jiao Tong Univ, Ctr Drug Safety & Policy Res, Xian, Shaanxi, Peoples R China
[3] Shaanxi Ctr Hlth Reform & Dev Res, Xian, Shaanxi, Peoples R China
[4] Shaheed Zulfiqar Ali Bhutto Med Univ, Dept Pathol, Islamabad, Pakistan
[5] King Faisal Univ, Coll Dent, Al Hufuf, Alahsa, Saudi Arabia
[6] Univ Sargodha Pakistan, Coll Pharm, Sargodha, Pakistan
关键词
dispensing of antibiotics; tuberculosis patients; dispensing practices; simulated client approach; community pharmacies;
D O I
10.3389/fpubh.2023.1241551
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background Pakistan is among top countries for antibiotic consumption around the globe and patients often receive antibiotics directly from community pharmacies. Thus, our aim was to assess the drug dispensing practices of pharmacies for presumed and confirmed tuberculosis by using standardized patients' method in Pakistan.Methods In this cross-sectional study, we adopted two standardized patient cases in pharmacies of three cities of Punjab. The first case involved a presumed tuberculosis patient presenting with 2-3 weeks of cough and fever (Case-1), and the second case involved a confirmed tuberculosis patient carrying microbiologically confirmed tuberculosis results (Case-2). The ideal management for Cases-1 and Case-2 is referral of standardized patients to a healthcare provider without dispensing antibiotics or steroids, or both. The differences in antibiotic use, steroid use, and the number of medicines dispensed in referred and non-referred patients between Case-1 and Case-2 were analyzed using descriptive statistics.Results Between April 1, 2020, and July 31, 2020, standardized patients completed 575 out of 598 interactions among community pharmacies in Lahore, Rawalpindi, and Sialkot. We recorded ideal management in 115 (37.7%) of the 305 Case-1 interactions and 130 (48.1%) of the 270 Case-2 interactions. Antibiotic dispensing was higher in Case-1, with 71 out of 305 instances (23.3%), than in Case-2 interactions, with 27 out of 270 instances (10.0%). Anti-tuberculosis drugs were dispensed to 1 patient in Case-1 (0.3%) and to 19 patients (7.0%) in Case-2.Conclusion Slightly more than one-third of pharmacies in Punjab, Pakistan, ideally managed patients with presumed tuberculosis, but almost half of them ideally managed cases of confirmed tuberculosis. The presence of confirmed diagnosis slightly changes the behavior in the correct management of patients.
引用
收藏
页数:8
相关论文
共 35 条
[1]   Assessment of without prescription antibiotic dispensing at community pharmacies in Hazara Division, Pakistan: A simulated client's study [J].
Ahmad, Tawseef ;
Khan, Faiz Ullah ;
Ali, Sayyad ;
Rahman, Asad Ur ;
Khan, Shujaat Ali .
PLOS ONE, 2022, 17 (02)
[2]   Knowledge on Multi-Drug Resistant Pathogens, Antibiotic Use and Self-Reported Adherence to Antibiotic Intake: A Population-Based Cross Sectional Survey From Pakistan [J].
Arshad, Hafsa ;
Gillani, Ali Hassan ;
Akbar, Jamshaid ;
Abbas, Huda ;
Ahmed, Asma Bashir ;
Gillani, Syed Nouman Hassan ;
Anum, Rabeea ;
Ji, Wenjing ;
Fang, Yu .
FRONTIERS IN PHARMACOLOGY, 2022, 13
[3]   Antibiotic stewardship program in Pakistan: a multicenter qualitative study exploring medical doctors' knowledge, perception and practices [J].
Atif, Muhammad ;
Ihsan, Beenish ;
Malik, Iram ;
Ahmad, Nafees ;
Saleem, Zikria ;
Sehar, Azka ;
Babar, Zaheer-ud-Din .
BMC INFECTIOUS DISEASES, 2021, 21 (01)
[4]  
cdn, About Us
[5]   Assessment of non-prescription antibiotic dispensing at community pharmacies in China with simulated clients: a mixed cross-sectional and longitudinal study [J].
Chang, Jie ;
Xu, Sen ;
Zhu, Shan ;
Li, Zongjie ;
Yu, Jiale ;
Zhang, Yu ;
Zu, Jian ;
Fang, Yu ;
Ross-Degnan, Dennis .
LANCET INFECTIOUS DISEASES, 2019, 19 (12) :1345-1354
[6]   Sale of antibiotics without a prescription at community pharmacies in urban China: a multicentre cross-sectional survey [J].
Chang, Jie ;
Ye, Dan ;
Lv, Bing ;
Jiang, Minghuan ;
Zhu, Shan ;
Yan, Kangkang ;
Tian, Yun ;
Fang, Yu .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2017, 72 (04) :1235-1242
[7]   Fluoroquinolones are associated with delayed treatment and resistance in tuberculosis: a systematic review and meta-analysis [J].
Chen, Tun-Chieh ;
Lu, Po-Liang ;
Lin, Chun-Yu ;
Lin, Wei-Ru ;
Chen, Yen-Hsu .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2011, 15 (03) :E211-E216
[8]   Measuring Quality Gaps in TB Screening in South Africa Using Standardised Patient Analysis [J].
Christian, Carmen S. ;
Gerdtham, Ulf-G. ;
Hompashe, Dumisani ;
Smith, Anja ;
Burger, Ronelle .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2018, 15 (04)
[9]   Drug-resistant tuberculosis in eastern Europe and central Asia: a time-series analysis of routine surveillance data [J].
Dadu, Andrei ;
Hovhannesyan, Arax ;
Ahmedov, Sevim ;
van der Werf, Marieke J. ;
Dara, Masoud .
LANCET INFECTIOUS DISEASES, 2020, 20 (02) :250-258
[10]   Can community pharmacists improve tuberculosis case finding? A mixed methods intervention study in India [J].
Daftary, Amrita ;
Satyanarayana, Srinath ;
Jha, Nita ;
Singh, Mugdha ;
Mondal, Shinjini ;
Vadnais, Caroline ;
Pai, Madhukar .
BMJ GLOBAL HEALTH, 2019, 4 (03)