Visible-Light Photoredox Catalysis in the Late-Stage Functionalization of Anticancer Agents

被引:7
|
作者
Singh, Praveen P. [1 ]
Srivastava, Vishal [2 ]
机构
[1] United Coll Engn & Res, Dept Chem, Prayagraj 211010, India
[2] Univ Allahabad, CMP Degree Coll, Dept Chem, Prayagraj 211002, India
来源
CHEMISTRYSELECT | 2023年 / 8卷 / 44期
关键词
Anticancer; Chemical biology; Photocatalysis; Photodynamic therapy; Visible-light; PHOTODYNAMIC THERAPY; CARBOXYLIC-ACIDS; N-HETEROCYCLES; CANCER; DRUGS; INDOLES;
D O I
10.1002/slct.202302732
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Visible light photocatalysis has several applications as a method of chemical transformation, with wide-ranging effects on the production of energy, preservation of the environment, the development of new drugs and human health. The light-induced sensitization of cofactors for photodynamic therapy in the treatment of cancer is a remarkable application with an influence on human health. The use of this photosensitization strategy in medicine has sparked interest in other photochemical techniques, such as photoredox catalysis, that could have an impact on biological research. The discovery of useful synthetic chemical transformations during the past ten years has made light-mediated catalysis a highly used method for chemical synthesis. This review will highlight the recent advances of visible-light photocatalysis through its application in anticancer activity. As a process of chemical change, visible light photocatalysis has many applications in the development of new drugs. Photodynamic therapy has a unique impact on human health for the treatment of cancer and application of this photosensitization technique in medicine has prompted interest in alternative photochemical methods. This review will highlight the recent advances of visible-light photocatalysis through its application in anticancer activity.image
引用
收藏
页数:19
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