The Role of Probiotics in Purine Metabolism, Hyperuricemia and Gout: Mechanisms and Interventions

被引：31
作者：
James, Armachius [1 ,2 ]
Ke, Hengming [3 ,4 ]
Yao, Ting [1 ,2 ]
Wang, Yousheng [1 ,2 ]
机构：
[1] Beijing Technol & Business Univ BTBU, Beijing Adv Innovat Ctr Food Nutr & Human Hlth, Beijing, Peoples R China
[2] Rizhao HUAWEI Inst Comprehens Hlth Ind, Rizhao, Peoples R China
[3] Univ N Carolina, Dept Biochem & Biophys, Chapel Hill, NC 27515 USA
[4] Univ N Carolina, Lineberger Comprehens Ctr, Chapel Hill, NC 27515 USA
来源：
FOOD REVIEWS INTERNATIONAL | 2023年 / 39卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Gout; hyperuricemia; probiotics; purines; urate; xanthine oxidase;
D O I：
10.1080/87559129.2021.1904412
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Hyperuricemia and gout are metabolic diseases characterized with high serum urate and impact human health significantly. Although some drugs have been developed to treat gout, hyperuricemia represents a substantial health problem. Reducing purine absorption through intestinal microbiota, which can be managed through intake of probiotics, emerges as a promising way to reverse elevated serum urate. Probiotics have shown several benefits such as immune modulation and improvement of intestinal functions. Therefore, this review briefly summarizes purine metabolism and molecular mechanisms for hyperuricemia and gout with the focus on recent development on the use of probiotics to alleviate hyperuricemia and gout.
引用
收藏
页码：261 / 277
页数：17
相关论文
共 119 条
  • [1] Association between serum uric acid (SUA) levels and metabolic syndrome (MetS) components in personnel of Shahroud University of Medical Sciences
    Abbasian, Maryam
    Ebrahimi, Hossein
    Delvarianzadeh, Mehrei
    Norouzi, Pirasteh
    Fazli, Mozhgan
    [J]. DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS, 2016, 10 (03) : 132 - 136
  • [2] The metabolic role of the gut microbiota in health and rheumatic disease: mechanisms and interventions
    Abdollahi-Roodsaz, Shahla
    Abramson, Steven B.
    Scher, Jose U.
    [J]. NATURE REVIEWS RHEUMATOLOGY, 2016, 12 (08) : 446 - 455
  • [3] ANGIOLILLI C, 2017, EPIGENOMICS-UK, V9, DOI DOI 10.2217/epi-2016-0136
  • [4] Biochemical and computational insights of adenosine deaminase inhibition by Epigallocatechin gallate
    Arun, K. G.
    Sharanya, C. S.
    Abhithaj, J.
    Sadasivan, C.
    [J]. COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 83
  • [5] Important food sources of fructose-containing sugars and incident gout: a systematic review and meta-analysis of prospective cohort studies
    Ayoub-Charette, Sabrina
    Liu, Qi
    Khan, Tauseef A.
    Au-Yeung, Fei
    Mejia, Sonia Blanco
    de Souza, Russell J.
    Wolever, Thomas M. S.
    Leiter, Lawrence A.
    Kendall, Cyril
    Sievenpiper, John L.
    [J]. BMJ OPEN, 2019, 9 (05):
  • [6] Effects of probiotic supplementation on inflammatory biomarkers and uremic toxins in non-dialysis chronic kidney patients: A double-blind, randomized, placebo-controlled trial
    Banos, Amanda de Faria
    Borges, Natalia A.
    Nakao, Lia Sumie
    Dolenga, Carla J.
    do Carmo, Flavia Lima
    Ferreira, Dennis de Carvalho
    Stenvinkel, Peter
    Bergman, Peter
    Lindholm, Bengt
    Mafra, Denise
    [J]. JOURNAL OF FUNCTIONAL FOODS, 2018, 46 : 378 - 383
  • [7] The role of xanthine oxidoreductase and uric acid in metabolic syndrome
    Battelli, Maria Giulia
    Bortolotti, Massimo
    Polito, Letizia
    Bolognesi, Andrea
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2018, 1864 (08): : 2557 - 2565
  • [8] Update on Importance of Diet in Gout
    Beyl, Randall N., Jr.
    Hughes, Laura
    Morgan, Sarah
    [J]. AMERICAN JOURNAL OF MEDICINE, 2016, 129 (11) : 1153 - 1158
  • [9] Renal Transport of Uric Acid: Evolving Concepts and Uncertainties
    Bobulescu, Alexandru
    Moe, Orson W.
    [J]. ADVANCES IN CHRONIC KIDNEY DISEASE, 2012, 19 (06) : 358 - 371
  • [10] Probiotic Supplementation in Chronic Kidney Disease: A Double-blind, Randomized, Placebo-controlled Trial
    Borges, Natalia A.
    Carmo, Flavia L.
    Stockler-Pinto, Milena B.
    de Brito, Jessyca S.
    Dolenga, Carla J.
    Ferreira, Dennis C.
    Nakao, Lia S.
    Rosado, Alexandre
    Fouque, Denis
    Mafra, Denise
    [J]. JOURNAL OF RENAL NUTRITION, 2018, 28 (01) : 28 - 36
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