Comparison of Ocular Biometric Measurements Using New Swept-source Optical-coherence Tomography, Low-coherence Reflectometry, A-Scan Biometry, and Autokeratometry

Purpose: We compared optical biometric measurements made using new swept-source optical-coherence tomography, low -co-herence reflectometry, autokeratometry, and A-scan biometry.Methods: In total, 86 eyes of 47 patients were included. Axial length, lens thickness, central corneal thickness, anterior chamber depth, and corneal curvature were measured using the Anterion (R) (Heidelberg Engineering, inc., Heidelberg, Germany) and Lenstar LS 900 (R) (Haag-Streit AG, Koeniz, Switzerland) platforms. Corneal curvature and axial length were measured using the Essilor AKR 750 (R) (Essilor instruments, France, Charenton-le-Pont) and PacScan 300A (R) (Sonomed Inc., Chicago, IL, USA) plat-forms, respectively. The evaluated biometric parameters were compared and verified; intraclass correlation coefficients and Bland-Altman plots were used to analyze statistical agreement.Results: The differences between the Anterion (R) and Lenstar LS 900 (R) platforms in terms of axial length, lens thickness, central corneal thickness, anterior chamber depth, and white-to-white diameter were-0.02 +/- 0.08, 0.08 +/- 0.13,-2.66 +/- 11.12, 0.05 +/- 0.12, and 0.08 +/- 0.26, respectively. All values were statistically significant. The mean corneal curvature between Anterion (R) and Lenstar LS 900 (R) had a statistically significant difference of-0.08 +/- 0.47, while the difference between the Anterion (R) and AKR 750 (R) platforms was not significant. Biometric parameters measured using an Anterion (R) and other devices showed a strong pos-itive correlation when assessed using Pearson's correlation analysis; there was good agreement between the results when ana-lyzed using intraclass correlation coefficients and Bland-Altman plots.Conclusions: Optical biometric measurements made using the Anterion (R) platform were not significantly different from those ob-tained using other devices, but there were significant differences compared to the Lenstar LS 900 (R) platform. Since these sig-nificant differences could influence decision making during intraocular lens selection for cataract surgery, the values are clinically useful for reference.J Korean Ophthalmol Soc 2023;64(4):287-295