Artificial Intelligence in Pharmaceutical and Healthcare Research

被引:50
作者
Bhattamisra, Subrat Kumar [1 ]
Banerjee, Priyanka [2 ]
Gupta, Pratibha [2 ]
Mayuren, Jayashree [3 ]
Patra, Susmita [2 ]
Candasamy, Mayuren [4 ]
机构
[1] GITAM, GITAM Sch Pharm, Dept Pharmacol, Visakhapatnam 530045, Andhra Pradesh, India
[2] Adamas Univ, Sch Med Sci, Dept Pharmaceut Technol, Kolkata 700126, West Bengal, India
[3] Int Med Univ, Sch Pharm, Dept Pharmaceut Technol, Kuala Lumpur 57000, Malaysia
[4] Int Med Univ, Sch Pharm, Dept Life Sci, Kuala Lumpur 57000, Malaysia
关键词
artificial intelligence; clinical trial; disease diagnosis; drug discovery; epidemic; personalized medicine; prediction; GENE-EXPRESSION; PREDICTION; DIAGNOSIS; DISEASE; MODEL; NETWORKS; SURVIVAL; TYPOLOGY; DESIGN; SYSTEM;
D O I
10.3390/bdcc7010010
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Artificial intelligence (AI) is a branch of computer science that allows machines to work efficiently, can analyze complex data. The research focused on AI has increased tremendously, and its role in healthcare service and research is emerging at a greater pace. This review elaborates on the opportunities and challenges of AI in healthcare and pharmaceutical research. The literature was collected from domains such as PubMed, Science Direct and Google scholar using specific keywords and phrases such as 'Artificial intelligence', 'Pharmaceutical research', 'drug discovery', 'clinical trial', 'disease diagnosis', etc. to select the research and review articles published within the last five years. The application of AI in disease diagnosis, digital therapy, personalized treatment, drug discovery and forecasting epidemics or pandemics was extensively reviewed in this article. Deep learning and neural networks are the most used AI technologies; Bayesian nonparametric models are the potential technologies for clinical trial design; natural language processing and wearable devices are used in patient identification and clinical trial monitoring. Deep learning and neural networks were applied in predicting the outbreak of seasonal influenza, Zika, Ebola, Tuberculosis and COVID-19. With the advancement of AI technologies, the scientific community may witness rapid and cost-effective healthcare and pharmaceutical research as well as provide improved service to the general public.
引用
收藏
页数:20
相关论文
共 156 条
[1]   A dynamic neural network model for predicting risk of Zika in real time [J].
Akhtar, Mahmood ;
Kraemer, Moritz U. G. ;
Gardner, Lauren M. .
BMC MEDICINE, 2019, 17 (01)
[2]   A Critical Review for Developing Accurate and Dynamic Predictive Models Using Machine Learning Methods in Medicine and Health Care [J].
Alanazi, Hamdan O. ;
Abdullah, Abdul Hanan ;
Qureshi, Kashif Naseer .
JOURNAL OF MEDICAL SYSTEMS, 2017, 41 (04)
[3]  
Albu A., 2012, Telemed. J. e-Health, V18, P446
[4]  
Amadin F. I., 2018, J EMERGING TRENDS EN, V9, P282
[5]  
[Anonymous], 2019, SYNTHETIC CONTROL AR
[6]   Radiomics with artificial intelligence for precision medicine in radiation therapy [J].
Arimura, Hidetaka ;
Soufi, Mazen ;
Kamezawa, Hidemi ;
Ninomiya, Kenta ;
Yamada, Masahiro .
JOURNAL OF RADIATION RESEARCH, 2019, 60 (01) :150-157
[7]  
Arlova Alena, 2022, J Pathol Inform, V13, P100007, DOI 10.1016/j.jpi.2022.100007
[8]  
Bajwa Junaid, 2021, Future Healthc J, V8, pe188, DOI 10.7861/fhj.2021-0095
[9]   Artificial Intelligence for the Prediction of Helicobacter Pylori Infection in Endoscopic Images: Systematic Review and Meta-Analysis Of Diagnostic Test Accuracy [J].
Bang, Chang Seok ;
Lee, Jae Jun ;
Baik, Gwang Ho .
JOURNAL OF MEDICAL INTERNET RESEARCH, 2020, 22 (09)
[10]   Comparison of classification accuracy using Cohen's Weighted Kappa [J].
Ben-David, Arie .
EXPERT SYSTEMS WITH APPLICATIONS, 2008, 34 (02) :825-832