Electrochemical Dopamine-Imprinted Sensor Based on Tio2 Nanoparticles and Polypyrrole-Chitosan Composites Modified Glassy Carbon Electrode

In this study, a composite material containing PY and CTS, as functional material, and dopamine, as template, was electrodeposited onto a GCE surface modified with NP from TiO2. The prepared MIP sensor was characterized by CV, SEM, FTIR and UV-vis techniques. The developed MIP matrix was used for dopamine detection, using DPV method. Diverse analytical parameters were optimized, such as: monomer, template, SE In the best conditions, the sensor response to dopamine was linear, in the concentration range from 1 x 10-6 to 1 x 10-5 mol/L-1. LOD was about 2.81.10-7 mol/L-1, and sensitivity was 3.202 mu A/L/mol-1/cm-2. Furthermore, the proposed MIP sensor showed good selectivity, repeatability, reproducibility and stability. Also, it was successfully applied for dopamine determination in urine samples.