In-situ synthesis of novel multifunctionally linked tin oxide on holy reduced graphene oxide: An electrocatalyst for antipsychotic drug sensing

Herein, we developed a novel electro-catalyst containing multifunctionally linked tin oxide on holy reduced graphene oxide (mf-SnO2/h-rGO) was prepared through a facile in situ hydrothermal method. The mf-SnO2/h-rGO coated onto the screen-printed carbon electrode (SPCE), which is used as a working electrode for the highly sensitive detection of phenothiazine (PTZ). The mf-SnO2/h-rGO/SPCE working electrode has an electroactive surface area of 0.66 cm2, peak to peak separation (& UDelta;Ep) of 122 mV, the ratio of anodic (Ipa) and cathodic (Ipc) current is 0.98, and charge transfer resistance (Rct) of 0.24 k & omega;. The prepared mf-SnO2/h-rGO catalyst shows a good detection limit (LOD) of 0.168 10-9 mole/L (Epa = 0.04 V) and 0.035 10-9 mole/L (Epa = 0.33 V) and an outstanding sensitivity of 1.44 & mu;A/mM cm2. The proposed sensor exhibits an acceptable stability, selectivity, repeatability and reproducibility. For real sample analysis, blood serum and urine samples were performed and mf-SnO2/h-rGO shows good recovery.