Seroprevalence of SARS-CoV-2 and Vaccination Coverage among Residents of a Lower-Middle-Class Population in the Federal District, Brazil

被引：1

作者：

de Brito, Raissa Nogueira ^{[1
]}

Teixeira, Ana Izabel Passarella ^{[2
]}

Gontijo, Carolina Carvalho ^{[3
]}

Faria, Rafael Da Silva ^{[3
]}

Ramalho, Walter Massa ^{[3
]}

Romero, Gustavo Adolfo Sierra ^{[3
]}

Castro, Manoel ^{[3
]}

Pessoa, Vitoria ^{[3
]}

Torres, Larissa Araujo ^{[3
]}

Leite, Larissa Pereira ^{[3
]}

Noronha, Elza Ferreira ^{[3
]}

Haddad, Rodrigo ^{[4
]}

de Araujo, Wildo Navegantes ^{[3
]}

机构：

[1] Univ Georgia, Dept Anthropol, Athens, GA 30602 USA

[2] Univ Fed Mato Grosso do Sul, Campus Paranaiba, BR-79500000 Paranaiba, MS, Brazil

[3] Univ Brasilia, Dept Trop Med, BR-70910900 Brasilia, DF, Brazil

[4] Hosp Univ Brasilia, Lab Diagnost Mol, BR-70910900 Brasilia, DF, Brazil

来源：

VACCINES | 2023年 / 11卷 / 05期

关键词：

seroprevalence; COVID-19; vaccination coverage; Brazil; COVID-19;

D O I：

10.3390/vaccines11050916

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Estimating seroprevalence and vaccination coverage against COVID-19 is crucial to the development of well-targeted public health policies at the local level. Here, we estimated seroprevalence and vaccination coverage in a lower-middle-class population in Brazil. We conducted an observational, cross-sectional, population-based survey from 24 September to 19 December 2021. CMIA tests were used to detect anti-SARS-CoV-2 IgG against the N-protein. The overall seroprevalence was 24.15% (177/733), and vaccination coverage was 91.40% (670/733); 72.09% (483/670) were fully vaccinated. Among vaccinated participants, seroprevalence was 24.77% (95% CI 21.50-28.04; 166/670), with a prevalence ratio (PR) of 1.03 (95% CI 0.98-1.08; p-value 0.131). Among participants who received an mRNA vaccine with S-based epitope (485), seroprevalence was 16.29% (95% CI 13.04-19.85; 79/485). Among unvaccinated participants, seroprevalence was 17.46% (95% CI 10.04-28.62; 11/63). Finally, in spite of the political climate and other possible causes for vaccine hesitancy, the positive Brazilian culture towards vaccination might have curbed hesitancy.

引用

页数：14

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