An Update on the Role of Circadian Rhythms in Sleep Disorders

被引:1
作者
Aziz, Namra [1 ]
Garg, Vipin Kumar [2 ]
Vinod, Yadav Rupali [1 ]
Gupta, Arpit [1 ]
Wal, Ankita [1 ]
Rathore, Shruti [3 ]
Wal, Pranay [1 ]
机构
[1] Pranveer Singh Inst Technol, Dept Pharm, Kanpur 209305, UP, India
[2] Meerut Inst Engn & Technol, Dept Pharmaceut Technol, Meerut 250005, UP, India
[3] LCIT Sch Pharm, Bilaspur 495220, Chhattisgarh, India
关键词
Circadian rhythm; sleep disorders; melatonin; metabolic syndrome; circadian rhythm disruptions; pathogenesis; RANDOMIZED CONTROLLED-TRIAL; MAJOR DEPRESSIVE DISORDER; BRIGHT LIGHT THERAPY; SHIFT-WORK DISORDER; PARKINSONS-DISEASE; WAKE SYNDROME; MELATONIN SECRETION; PRACTICE PARAMETERS; DIURNAL PREFERENCE; MOOD DISORDERS;
D O I
10.2174/1574885518666230818102714
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background The comprehension of the molecular, cellular, and biological mechanisms that underlie the management of the sleep-wake cycle, as well as the effects of circadian disruption on health and illness, has made significant strides.Methods An extensive literature review was done from the standard databases such as Scopus, Elsevier, and PubMed using standard keywords "Circadian rhythm", and "sleep disorders". In this section, we examined circadian biology and provided adetailed description of the pathogenesis, clinical characteristics, diagnosis, and management of the most typical Circadian rhythm sleep disorders (CRSDs) seen in clinical practice.Conclusion It can be concluded that the central circadian rhythm mechanism may be altered, or the intrinsic circadian clock and the environment may not be in sync, to produce circadian rhythm sleep disorders. As a consequence, we must focus on modifying our way of life in a constructive and healthy way. Even while the lifestyle is based on personal preferences and identities, it is important to examine it in isolation from its sociocultural environment.
引用
收藏
页码:302 / 316
页数:15
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