Paths to organ damage and risk factors in AKI

被引：6
作者：
Ostermann, Marlies [1 ]
Rosner, Mitchell H. [2 ]
机构：
[1] Guys & St Thomas NHS Fdn Hosp, Kings Coll London, Dept Crit Care & Nephrol, London, England
[2] Univ Virginia Hlth, Div Nephrol, Charlottesville, VA USA
来源：
NATURE REVIEWS NEPHROLOGY | 2023年 / 19卷 / 02期
关键词：
ACUTE KIDNEY INJURY;
D O I：
10.1038/s41581-022-00669-7
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Acute kidney injury (AKI) is a multifactorial syndrome with a complex pathophysiology including different inflammatory cells and mediators. Current research focuses on identifying key contributing pathways, determining high-risk groups, characterizing AKI sub-phenotypes and investigating strategies for therapeutic interventions.
引用
收藏
页码：77 / 78
页数：2
相关论文
共 10 条
  • [1] Acute kidney injury in patients treated with immune checkpoint inhibitors
    Gupta, Shruti
    Short, Samuel A. P.
    Sise, Meghan E.
    Prosek, Jason M.
    Madhavan, Sethu M.
    Soler, Maria Jose
    Ostermann, Marlies
    Herrmann, Sandra M.
    Abudayyeh, Ala
    Anand, Shuchi
    Glezerman, Ilya
    Motwani, Shveta S.
    Murakami, Naoka
    Wanchoo, Rimda
    Ortiz-Melo, David, I
    Rashidi, Arash
    Sprangers, Ben
    Aggarwal, Vikram
    Malik, A. Bilal
    Loew, Sebastian
    Carlos, Christopher A.
    Chang, Wei-Ting
    Beckerman, Pazit
    Mithani, Zain
    Shah, Chintan, V
    Renaghan, Amanda D.
    De Seigneux, Sophie
    Campedel, Luca
    Kitchlu, Abhijat
    Shin, Daniel Sanghoon
    Rangarajan, Sunil
    Deshpande, Priya
    Coppock, Gaia
    Eijgelsheim, Mark
    Seethapathy, Harish
    Lee, Meghan D.
    Strohbehn, Ian A.
    Owen, Dwight H.
    Husain, Marium
    Garcia-Carro, Clara
    Bermejo, Sheila
    Lumlertgul, Nuttha
    Seylanova, Nina
    Flanders, Lucy
    Isik, Busra
    Mamlouk, Omar
    Lin, Jamie S.
    Garcia, Pablo
    Kaghazchi, Aydin
    Khanin, Yuriy
    [J]. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 (10)
  • [2] Long-term kidney function of patients discharged from hospital after an intensive care admission: observational cohort study
    Haines, Ryan W.
    Powell-Tuck, Jonah
    Leonard, Hugh
    Crichton, Siobhan
    Ostermann, Marlies
    [J]. SCIENTIFIC REPORTS, 2021, 11 (01)
  • [3] The multiple functions and mechanisms of osteopontin
    Icer, Mehmet Arif
    Gezmen-Karadag, Makbule
    [J]. CLINICAL BIOCHEMISTRY, 2018, 59 : 17 - 24
  • [4] Effect of Clinical Decision Support With Audit and Feedback on Prevention of Acute Kidney Injury in Patients Undergoing Coronary Angiography A Randomized Clinical Trial
    James, Matthew T.
    Har, Bryan J.
    Tyrrell, Benjamin D.
    Faris, Peter D.
    Tan, Zhi
    Spertus, John A.
    Wilton, Stephen B.
    Ghali, William A.
    Knudtson, Merril L.
    Sajobi, Tolulope T.
    Pannu, Neesh, I
    Klarenbach, Scott W.
    Graham, Michelle M.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2022, 328 (09): : 839 - 849
  • [5] Lung-kidney interactions in critically ill patients: consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup
    Joannidis, Michael
    Forni, Lui G.
    Klein, Sebastian J.
    Honore, Patrick M.
    Kashani, Kianoush
    Ostermann, Marlies
    Prowle, John
    Bagshaw, Sean M.
    Cantaluppi, Vincenzo
    Darmon, Michael
    Ding, Xiaoqiang
    Fuhrmann, Valentin
    Hoste, Eric
    Husain-Syed, Faeq
    Lubnow, Matthias
    Maggiorini, Marco
    Meersch, Melanie
    Murray, Patrick T.
    Ricci, Zaccaria
    Singbartl, Kai
    Staudinger, Thomas
    Welte, Tobias
    Ronco, Claudio
    Kellum, John A.
    [J]. INTENSIVE CARE MEDICINE, 2020, 46 (04) : 654 - 672
  • [6] Identification of kidney injury-released circulating osteopontin as causal agent of respiratory failure
    Khamissi, Fatima Zohra
    Ning, Liang
    Kefaloyianni, Eirini
    Dun, Hao
    Arthanarisami, Akshayakeerthi
    Keller, Amy
    Atkinson, Jeffrey J.
    Li, Wenjun
    Wong, Brian
    Dietmann, Sabine
    Lavine, Kory
    Kreisel, Daniel
    Herrlich, Andreas
    [J]. SCIENCE ADVANCES, 2022, 8 (08)
  • [7] A contemporary simple risk score for prediction of contrast-associated acute kidney injury after percutaneous coronary intervention: derivation and validation from an observational registry
    Mehran, Roxana
    Owen, Ruth
    Chiarito, Mauro
    Bober, usman
    Sartori, Samantha
    Cao, Davide
    Nicolas, Johny
    Pivato, Carlo Andrea
    Nordin, Matteo
    Krishnan, Prakash
    Kini, Annapoorna
    Shanna, Samin
    Pocock, Stuart
    Dangas, George
    [J]. LANCET, 2021, 398 (10315) : 1974 - 1983
  • [8] Onco-nephrology: what the intensivist needs to know
    Rosner, Mitchell H.
    Darmon, Michael
    Ostermann, Marlies
    [J]. INTENSIVE CARE MEDICINE, 2022, 48 (09) : 1234 - 1236
  • [9] Immune-mediated tubule atrophy promotes acute kidney injury to chronic kidney disease transition
    Xu, Leyuan
    Guo, Jiankan
    Moledina, Dennis G.
    Cantley, Lloyd G.
    [J]. NATURE COMMUNICATIONS, 2022, 13 (01)
  • [10] Acute kidney injury and maladaptive tubular repair leading to renal fibrosis
    Yu, Samuel M. -W.
    Bonventre, Joseph V.
    [J]. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2020, 29 (03) : 310 - 318
1