Deciphering the suppressive immune microenvironment of prostate cancer based on CD4+regulatory T cells: Implications for prognosis and therapy prediction

被引：53
作者：
Ge, Qintao [1 ,2 ,3 ]
Zhao, Zhijie [4 ]
Li, Xiao [1 ,2 ,3 ]
Yang, Feixiang [1 ,2 ,3 ]
Zhang, Meng [1 ,2 ,3 ]
Hao, Zongyao [1 ,2 ,3 ]
Liang, Chaozhao [1 ,2 ,3 ,5 ]
Meng, Jialin [1 ,2 ,3 ,5 ]
机构：
[1] Anhui Med Univ, Affiliated Hosp 1, Dept Urol, Hefei 230001, Peoples R China
[2] Anhui Med Univ, Inst Urol, Hefei, Peoples R China
[3] Anhui Med Univ, Anhui Prov Key Lab Urol & Androl Dis Res & Med Tra, Hefei, Peoples R China
[4] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 9, Dept Plast & Reconstruct Surg, Sch Med, Shanghai, Peoples R China
[5] Anhui Prov Inst Translat Med, Hefei, Peoples R China
来源：
CLINICAL AND TRANSLATIONAL MEDICINE | 2024年 / 14卷 / 01期
关键词：
D O I：
10.1002/ctm2.1552
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：7
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共 10 条
[1]   Transforming Growth Factor-β Signaling in Immunity and Cancer [J].
Batlle, Eduard ;
Massague, Joan .
IMMUNITY, 2019, 50 (04) :924-940
[2]   Randomized, Double-Blind, Phase III Trial of Ipilimumab Versus Placebo in Asymptomatic or Minimally Symptomatic Patients With Metastatic Chemotherapy-Naive Castration-Resistant Prostate Cancer [J].
Beer, Tomasz M. ;
Kwon, Eugene D. ;
Drake, Charles G. ;
Fizazi, Karim ;
Logothetis, Christopher ;
Gravis, Gwenaelle ;
Ganju, Vinod ;
Polikoff, Jonathan ;
Saad, Fred ;
Humanski, Piotr ;
Piulats, Josep M. ;
Gonzalez Mella, Pablo ;
Ng, Siobhan S. ;
Jaeger, Dirk ;
Parnis, Francis X. ;
Franke, Fabio A. ;
Puente, Javier ;
Carvajal, Roman ;
Sengelov, Lisa ;
McHenry, M. Brent ;
Varma, Arvind ;
van den Eertwegh, Alfonsus J. ;
Gerritsen, Winald .
JOURNAL OF CLINICAL ONCOLOGY, 2017, 35 (01) :40-+
[3]   Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer [J].
Carver, Brett S. ;
Chapinski, Caren ;
Wongvipat, John ;
Hieronymus, Haley ;
Chen, Yu ;
Chandarlapaty, Sarat ;
Arora, Vivek K. ;
Le, Carl ;
Koutcher, Jason ;
Scher, Howard ;
Scardino, Peter T. ;
Rosen, Neal ;
Sawyers, Charles L. .
CANCER CELL, 2011, 19 (05) :575-586
[4]   Mutant p53 in cancer: from molecular mechanism to therapeutic modulation [J].
Chen, Xiaohua ;
Zhang, Taotao ;
Su, Wei ;
Dou, Zhihui ;
Zhao, Dapeng ;
Jin, Xiaodong ;
Lei, Huiwen ;
Wang, Jing ;
Xie, Xiaodong ;
Cheng, Bo ;
Li, Qiang ;
Zhang, Hong ;
Di, Cuixia .
CELL DEATH & DISEASE, 2022, 13 (11)
[5]   Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells [J].
Downs-Canner, Stephanie ;
Berkey, Sara ;
Delgoffe, Greg M. ;
Edwards, Robert P. ;
Curiel, Tyler ;
Odunsi, Kunle ;
Bartlett, David L. ;
Obermajer, Natass .
NATURE COMMUNICATIONS, 2017, 8
[6]   Immunogenomics Analysis Reveals that TP53 Mutations Inhibit Tumor Immunity in Gastric Cancer [J].
Jiang, Zehang ;
Liu, Zhixian ;
Li, Mengyuan ;
Chen, Cai ;
Wang, Xiaosheng .
TRANSLATIONAL ONCOLOGY, 2018, 11 (05) :1171-1187
[7]   Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy [J].
Jiao, Shiping ;
Subudhi, Sumit K. ;
Aparicio, Ana ;
Ge, Zhongqi ;
Guan, Baoxiang ;
Miura, Yuji ;
Sharma, Padmanee .
CELL, 2019, 179 (05) :1177-+
[8]   Inherited TP53 Variants and Risk of Prostate Cancer [J].
Maxwell, Kara N. ;
Cheng, Heather H. ;
Powers, Jacquelyn ;
Gulati, Roman ;
Ledet, Elisa M. ;
Morrison, Casey ;
Le, Anh ;
Hausler, Ryan ;
Stopfer, Jill ;
Hyman, Sophie ;
Kohlmann, Wendy ;
Naumer, Anne ;
Vagher, Jennie ;
Greenberg, Samantha E. ;
Naylor, Lorraine ;
Laurino, Mercy ;
Konnick, Eric Q. ;
Shirts, Brian H. ;
AlDubayan, Saud H. ;
Van Allen, Eliezer M. ;
Nguyen, Bastien ;
Vijai, Joseph ;
Abida, Wassim ;
Carlo, Maria, I ;
Dubard-Gault, Marianne ;
Lee, Daniel J. ;
Maese, Luke D. ;
Mandelker, Diana ;
Montgomery, Bruce ;
Morris, Michael J. ;
Nicolosi, Piper ;
Nussbaum, Robert L. ;
Schwartz, Lauren E. ;
Stadler, Zsofia ;
Garber, Judy E. ;
Offit, Kenneth ;
Schiffman, Joshua D. ;
Nelson, Peter S. ;
Sartor, Oliver ;
Walsh, Michael F. ;
Pritchard, Colin C. .
EUROPEAN UROLOGY, 2022, 81 (03) :243-250
[9]   Immune response drives outcomes in prostate cancer: implications for immunotherapy [J].
Meng, Jialin ;
Zhou, Yujie ;
Lu, Xiaofan ;
Bian, Zichen ;
Chen, Yiding ;
Zhou, Jun ;
Zhang, Li ;
Hao, Zongyao ;
Zhang, Meng ;
Liang, Chaozhao .
MOLECULAR ONCOLOGY, 2021, 15 (05) :1358-1375
[10]   Role of PI3K-AKT-mTOR Pathway as a Pro-Survival Signaling and Resistance-Mediating Mechanism to Therapy of Prostate Cancer [J].
Pungsrinont, Thanakorn ;
Kallenbach, Julia ;
Baniahmad, Aria .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (20)
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