Phytoconstituent-Loaded Nanofibrous Meshes as Wound Dressings: A Concise Review

被引:8
作者
Sharma, Ameya [1 ]
Dheer, Divya [1 ,2 ]
Singh, Inderbir [3 ]
Puri, Vivek [1 ]
Kumar, Pradeep [4 ]
机构
[1] Chitkara Univ, Chitkara Sch Pharm, Baddi 174103, Himachal Prades, India
[2] Inst Nano Sci & Technol, Chem Biol Unit, Knowledge City, Sect 81, Mohali 140306, Punjab, India
[3] Chitkara Univ, Chitkara Coll Pharm, Rajpura 140401, Punjab, India
[4] Univ Witwatersrand, Fac Hlth Sci, Sch Therapeut Sci, Dept Pharm & Pharmacol, ZA-2050 Johannesburg, South Africa
关键词
phytoconstituents; nanofibers; wound; wound healing; wound dressings; polysaccharides; ALOE-VERA; ELECTROSPUN FIBERS; SCAFFOLD; NANOPARTICLES; MEMBRANES; MAT;
D O I
10.3390/pharmaceutics15041058
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In the past, wounds were treated with natural materials, but modern wound dressings include functional elements to expedite the process of healing and to improve skin recovery. Due to their exceptional properties, nanofibrous wound dressings are now the most cutting-edge and desirable option. Similar in structure to the skin's own extracellular matrix (ECM), these dressings can promote tissue regeneration, wound fluid transportation, and air ductility for cellular proliferation and regeneration owing to their nanostructured fibrous meshes or scaffolds. Many academic search engines and databases, such as Google Scholar, PubMed, and Sciencedirect, were used to conduct a comprehensive evaluation of the literature for the purposes of this investigation. Using the term "nanofibrous meshes" as a keyword, this paper focuses on the importance of phytoconstituents. This review article summarizes the most recent developments and conclusions from studies on bioactive nanofibrous wound dressings infused with medicinal plants. Several wound-healing methods, wound-dressing materials, and wound-healing components derived from medicinal plants were also discussed.
引用
收藏
页数:24
相关论文
共 129 条
  • [1] Abudula T., 2021, U.S. Patent, Patent No. [11124897B1, 11124897]
  • [2] Electrospun Conducting Polymers: Approaches and Applications
    Acosta, Mariana
    Santiago, Marvin D. D.
    Irvin, Jennifer A. A.
    [J]. MATERIALS, 2022, 15 (24)
  • [3] A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications
    Ahmad, Awais
    Mubarak, N. M.
    Jannat, Fakiha Tul
    Ashfaq, Tayyaba
    Santulli, Carlo
    Rizwan, Muhammad
    Najda, Agnieszka
    Bin-Jumah, May
    Abdel-Daim, Mohamed M.
    Hussain, Shahid
    Ali, Shafaqat
    [J]. PROCESSES, 2021, 9 (01) : 1 - 27
  • [4] Applications of Electrospun Drug-Eluting Nanofibers in Wound Healing: Current and Future Perspectives
    Akombaetwa, Nakamwi
    Bwanga, Alick
    Makoni, Pedzisai Anotida
    Witika, Bwalya A.
    [J]. POLYMERS, 2022, 14 (14)
  • [5] Design, synthesis, in silico and antibacterial evaluation of curcumin derivatives loaded nanofiber as potential wound healing agents
    Alabdali, Aya Yaseen Mahmood
    Khalid, Raghda
    Kzar, Marwah
    Ezzat, Mohammed Oday
    Huei, Gan Min
    Hsia, Tan Wei
    Mogana, R.
    Rahman, H.
    Razik, Basma M. Abd
    Issac, Praveen Kumar
    Chinnappan, Sasikala
    Khalivulla, Shaik Ibrahim
    [J]. JOURNAL OF KING SAUD UNIVERSITY SCIENCE, 2022, 34 (07)
  • [6] Hyaluronic acid-based nanoplatforms for Doxorubicin: A review of stimuli-responsive carriers, co-delivery and resistance suppression
    Ashrafizadeh, Milad
    Mirzaei, Sepideh
    Gholami, Mohammad Hossein
    Hashemi, Farid
    Zabolian, Amirhossein
    Raei, Mehdi
    Hushmandi, Kiavash
    Zarrabi, Ali
    Voelcker, Nicolas H.
    Aref, Amir Reza
    Hamblin, Michael R.
    Varma, Rajender S.
    Samarghandian, Saeed
    Arostegi, I. J.
    Alzola, M.
    Kumar, Alan Prem
    Thakur, Vijay Kumar
    Nabavi, Noushin
    Makvandi, Pooyan
    Tay, Franklin R.
    Orive, Gorka
    [J]. CARBOHYDRATE POLYMERS, 2021, 272
  • [7] Wound healing potential of licorice extract in rat model: Antioxidants, histopathological, immunohistochemical and gene expression evidences
    Assar, Doaa H.
    Elhabashi, Nagwan
    Mokhbatly, Abd-Allah A.
    Ragab, Amany E.
    Elbialy, Zizy I.
    Rizk, Sally A.
    Albalawi, Aishah E.
    Althobaiti, Norah A.
    Al Jaouni, Soad
    Atiba, Ayman
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2021, 143
  • [8] Optimal Aloe vera encapsulated PCL/Gel nanofiber design for skin substitute application and the evaluation of its in vivo implantation
    Baghersad, Somayeh
    Hivechi, Ahmad
    Bahrami, S. Hajir
    Milan, Peiman Brouki
    Siegel, Ronald A.
    Amoupour, Moein
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2022, 74
  • [9] Development of biodegradable electrospun gelatin/aloe-vera/poly (ε-caprolactone) hybrid nanofibrous scaffold for application as skin substitutes
    Baghersad, Somayeh
    Bahrami, S. Hajir
    Mohammadi, Marziyeh Ranjbar
    Mojtahedi, Mohammad Reza Mohaddes
    Milan, Peiman Brouki
    [J]. MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2018, 93 : 367 - 379
  • [10] Rotary Jet Spinning (RJS']JS): A Key Process to Produce Biopolymeric Wound Dressings
    Bahu, Juliana O.
    de Andrade, Lucas Melo R.
    Crivellin, Sara
    Khouri, Nadia G.
    Sousa, Sara O.
    Fernandes, Luiza M. I.
    Souza, Samuel D. A.
    Concha, Luz S. Cardenas
    Schiavon, Maria I. R. B.
    Benites, Cibelem I.
    Severino, Patricia
    Souto, Eliana B.
    Concha, Viktor O. Cardenas
    [J]. PHARMACEUTICS, 2022, 14 (11)