Less Is More? Antibiotic Treatment Duration in Pseudomonas aeruginosa Ventilator-Associated Pneumonia

被引：22
作者：
Albin, Owen R. [1 ]
Kaye, Keith S. [2 ]
McCreary, Erin K. [3 ]
Pogue, Jason M. [4 ]
机构：
[1] Univ Michigan, Dept Internal Med, Med Sch, 1500 E Med Ctr Dr, Ann Arbor, MI 48109 USA
[2] Univ Med & Dent New Jersey, Dept Internal Med, Div Infect Dis Allergy & Immunol, New Brunswick, NJ USA
[3] Univ Pittsburgh, Sch Med, Dept Med, Div Infect Dis, Pittsburgh, PA 15213 USA
[4] Univ Michigan, Coll Pharm, Dept Clin Pharm, 428 Church St, Ann Arbor, MI 48109 USA
来源：
CLINICAL INFECTIOUS DISEASES | 2023年 / 76卷 / 04期
关键词：
ventilator-associated pneumonia; Pseudomonas aeruginosa; hospital-acquired pneumonia; non-fermenting gram-negative bacilli; THERAPY; ADULTS;
D O I：
10.1093/cid/ciac784
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Despite multiple clinical trials on the issue, the optimal antimicrobial treatment durations for ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa requires further study. Recommended antimicrobial treatment durations for ventilator-associated pneumonia (VAP) caused by Pseudomonas aeruginosa have evolved over the past few decades. In this Viewpoint, we provide a narrative review of landmark trials investigating antimicrobial treatment durations for VAP caused by P. aeruginosa, and appraise iterations of expert consensus guidelines based on these data. We highlight strengths and weaknesses of existing data on this topic and provide recommendations for future avenues of study.
引用
收藏
页码：745 / 749
页数：5
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